cathepsin


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Related to cathepsin: Cathepsin C

cathepsin

[kə′thep·sən]
(biochemistry)
Any of several proteolytic enzymes occurring in animal tissue that hydrolyze high-molecular-weight proteins to proteoses and peptones.
References in periodicals archive ?
Calpain and cathepsin activities in postmortem fish and meat muscles.
SLPI has antiprotease activity and plays an important role in neutralizing enzymes such as neutrophil elastase to prevent excessive tissue damage during inflammation.[5] For this reason, we investigated if the cathepsin K activity of BALF can be inhibited by SLPI.
Cathepsin L activity was measured at both the optimum pH for enzyme activity (pH 5.5) and ultimate pH (Figure 2).
Cathepsins, which are lysosomal proteases known to degrade unwanted intracellular or endocytosed proteins, reportedly play functional roles in the pathogenesis of heart disease by contributing to matrix turnover, chamber dilation, and structural remodeling [12].
These data suggest that high-level DCA could induce S1PR2 expression in macrophages, thus initiating the activation of related downstream signaling, which may contribute to the cathepsin B release and inflammasome activation.
Waltenberger, "Cathepsin enzymes and cystatin C: do they play a role in positive arterial remodeling?" Stroke, vol.
Measurement of cathepsins B and L enzyme activity: The method used to obtain the fractions enriched with lysosomes (FEL) and supernatant (cytosolic) fraction was modified from Ichihara et al.
Evidence for a founder mutation in the cathepsin C gene in three families with Papillon-Lefevre syndrome.
Results: The highest number of metastatic axillary lymph nodes and the highest rate of cathepsin D staining were statistically found in the cases with positive axillary lymph node metastasis and extranodal tumor invasion.
Hiraiwa, "Cathepsin A/protective protein: an unusual lysosomal multifunctional protein," Cellular and Molecular Life Sciences, vol.
Edman et al., "Tear cathepsin s as a candidate biomarker for sjogren's syndrome," Arthritis and Rheumatology, vol.