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VBY-036 is an optimized cathepsin S inhibitor that is a potent, competitive and reversible inhibitor of cathepsin S.
The data were presented in a poster, titled "Efficacy of a Spectrum-Selective Cathepsin Inhibitor in a Mouse Model of Bone Cancer," by Holsinger, et al.
Application to start phase I trials on cathepsin K for treating skeletal disorders filed with the European regulatory authority
Virobay was founded upon a rich industry legacy of intensive research and development focused on the cathepsin family of cysteine proteases.
Washington, March 8 ( ANI ): Researchers have confirmed the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer's disease (AD), at least in an animal model.
Species-specific distribution of cathepsin E in mammalian blood cells.
Medivir AB (STO:MVIRB), a research-based specialty pharmaceutical company focused on infectious diseases, announced today that it will file an application to a European regulatory agency to begin phase I clinical trials with MIV-711, a cathepsin K inhibitor for the treatment of bone disorders such as osteoporosis, osteoarthritis or bone metastases.
29, CA 19-9, CA 125, Calcitonin, Cathepsin, CEA, Chromogranin, Colon-Specific Antigen, Cytokeratins, Estrogen Receptor, Ferritin, Gastrin, HCG, Insulin, Interferons, Interleukins, Lymphocyte Subtyping, Neuron-Specific Enolase, Nucleolar, Occult Blood, Oncogenes, Pancreatic Oncofetal Antigen, Pap Smear, Parathyroid Hormone, Progesterone Receptor, Prostatic Acid Phosphatase, Prostatic Specific Antigen, S-100 Protein, Serotonin, Sialic Acid, Squamous Cell Carcinoma Ag, TDT, Thymidine Kinase, Thyroglobulin, Tissue Polypeptide Antigen, and others.
Instead, E64d appears to lower brain AB by inhibiting the B-secretase activity of another protease, Cathepsin B.
Pipeline candidates fall under major therapeutic classes such as osteoclast activity inhibitors, osteoclast activity promoters, bone anabolic agents, SERMs, SARMs, RANKL inhibitors, dual acting bone agents, PTH release stimulator, cathepsin K inhibitor, bone morphogenetic protein signaler, aminobisphosphonate, DKK1 Protein inhibitor and osteoblast level promotor
Cathepsin Test Volume and Diagnostics Sales Forecast by Market Segment U.