caveolae

[kə′vē·ə·lē]

(cell and molecular biology)

Tiny indentations in the cell surface membrane which trap fluids during the process of micropinocytosis.

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References in periodicals archive ?

Caveolae, which are a special type of lipid raft, are small (50-100 nm) invaginations of the plasma membrane in many vertebrate cell types, especially in endothelial cells and adipocytes.

Comparison of Caveolin-1 and PSA in Prostate Adenocarcinoma/Prostat Adenokarsinomunda Caveolin-1 ve PSA'nin Karsilastirilmasi

For instance, Clathrin-coated Pit-mediated receptor internalization (caveolae pathway), at least in some cases, has been reported to traffic ADC to the cells.

Antibody-Drug Conjugates: Possibilities and Challenges

The eNOS is located in the caveolae and T-tubes, whereas the nNOS is located in the sarcoplasmic reticulum.

The Role of Nitric Oxide Related Therapeutics in the Treatment of Cardiovascular Pathologies

Filipin (caveolae-mediated endocytosis inhibitor) was used to show that transferrin-PLGA NPs were endocytosed via caveolae pathway.

Targeted Therapeutic Nanoparticles: An Immense Promise to Fight against Cancer

Caveolae Cholesterol Is Actively Consumed in Cholesterol Efflux from the Cells.

Intracellular and Plasma Membrane Events in Cholesterol Transport and Homeostasis

Caveolae are plasma membrane microdomains, composed by cholesterol, sphingolipids, and different coat proteins named caveolins, considered anchor points to molecules (in this context, insulin receptor and GLUT4), facilitating their interaction, in order to activate cell signaling and transport [91-93].

Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue

Pabelick, "Inflammation, caveolae and CD38-mediated calcium regulation in human airway smooth muscle," Biochimica et Biophysica Acta, vol.

CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

Rapid insulindependent endocytosis of the insulin receptor by caveolae in primary adipocytes.

Adipogenic Effects and Gene Expression Profiling of Firemaster[R] 550 Components in Human Primary Preadipocytes

Caveolin-1 (Cav-1), a 22-kD protein of 178 amino acids and a member of the caveolin family (Cav-1, 2, and 3), is the highly conserved and essential component of caveolae [4].

Prognostic Value of Metastatic Tumoral Caveolin-1 Expression in Patients with Resected Gastric Cancer

Oxidative stress generated by the Hhcy and LDL ox (ROS and carbonyl adducts) reduced the availability of NO and alter structures and functions of caveolae, which are transcellular transport system of various molecules, including amino acids (Met), in endothelial cells [70].

Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring

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