cell permeability

Cell permeability

The permitting or activating of the passage of substances into, out of, or through cells, or from one cell to another. These materials traverse either the cell surface that demarcates the living cytoplasm from the extracellular space or the boundaries between adjacent cells. In many cases the materials also traverse the cell wall. See Cell walls (plant)

The cell can control many properties of its membranes, including those related to permeability. Control can be exerted in the following ways: (1) by varying the number and variety of membranes; (2) by varying the specific nature of the lipid components in the membrane; (3) by varying the glycocalyx proteins or lipid-associated sugar molecules on the outside of the cell, or the membrane-associated proteins on the inside; (4) by causing large areas of membrane to flow from one place to another, or to fold, indent, evert, or pinch off, carrying with these movements substances bound to one or the other surface of the membrane, or embedded in it; (5) by selectively moving integral membrane proteins in the plane of the membrane, allowing these proteins to carry with them substances, particles, molecules, or other materials bound to them; (6) by varying the properties of a single integral membrane protein or of a closely associated group of them so as to allow or prevent the passage across the membrane of substances such as ions or proteins of a specific character. See Cell membranes

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.

cell permeability

[′sel pər·mē·ə′bil·əd·ē]
(cell and molecular biology)
The permitting or activating of the passage of substances into, out of, or through cells.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Initiated in 2013, the Merck collaboration leverages Ra Pharma's Extreme Diversity platform aimed at producing macrocyclic peptides that are designed to have the diversity and specificity of antibodies, while retaining the pharmacologic attributes of small molecules, with the potential to allow for the rapid identification, design, and development of drug-like peptides with high stability, bioavailability, cell permeability, and potency.
In this study, we found that the expression of occludin and ZO-1 gradually decreased with the elongation of hypoxia time, meanwhile cell permeability was increased after 24-h exposure to hypoxia, both being significantly different compared to the control group.
Endothelial dysfunction is strongly associated with cardiovascular risk factors such as atherosclerosis, elevated level of low density lipoprotein oxidation, cytokine elaboration, up regulation of adhesion molecules, increased cell permeability, platelet aggregation as well as proliferation and migration of vascular smooth muscles.
Kodadek, "A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds," Nature Protocols, vol.
Singh, "HIV-1 Tat C phosphorylates VE-cadherin complex and increases human brain microvascular endothelial cell permeability," BMC Neuroscience, vol.
All these results are with subsequent increasing cell permeability. TXL partly normalized ox-LDL-induced disruption and distribution of tight junction proteins and prevented ox-LDL-induced hyperpermeability by modulating the activation of ERK1/2 pathway.
7a indicates the intensity results of total nuclei, cell permeability, mitochondrial membrane potential (MMP) and cytochrome c.
The main vascular endothelial cell permeability modulation is contraction caused by the interaction of actin and myosin.
Finally, from in vitro experiments it is known that IL-17A increases endothelial cell permeability at 10 or 100ng/mL doses [78, 79].
Therapeutic ultrasound increases cell permeability by setting up the cavitations, thus aiding in cell communication across articular membrane and linings.