cell-mediated immunity

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Related to cell-mediated immune response: cellular immunity, humoral immune response

cell-mediated immunity

[¦sel ¦mē·dē‚ād·əd i′myü·nəd·ē]
(immunology)
Immune responses produced by the activities of T cells rather than by immunoglobulins.
References in periodicals archive ?
Further, we provided evidence for a murine beryllium-specific, cell-mediated immune response following cutaneous application of BeO and BeS[O.
ChronVac-C([R]) is a therapeutic DNA vaccine being given to individuals already infected with hepatitis C virus with the aim to clear the infection by boosting a cell-mediated immune response against the virus.
BiovaxID is an active immunotherapeutic that stimulates the production of anti-tumor antibodies and induces a cell-mediated immune response to cancerous B-lymphocytes but not to normal B-lymphocytes.
BiovaxID is an active immunotherapeutic which stimulates the production of anti-tumor antibodies and induces a cell-mediated immune response to cancerous B-lymphocytes but not to normal B-lymphocytes.
Previous studies in animals and simple model organisms over the past 85 years have supported the notion that calorie restriction can increase the lifespan by reducing inflammation and other chronic disease risk factors, but with mixed results about whether it has a negative or null effect on cell-mediated immune responses," said first and corresponding author Simin Nikbin Meydani, D.
Although it is likely that the presence of Eimeria oocysts and endemic viruses varies qualitatively and quantitatively between flocks and, by extension, varies between different used litter types, we believe that these data provide evidence that exposure of growing chicks to used poultry litter stimulates humoral and cell-mediated immune responses, presumably due to contact with contaminating enteric pathogens.
receptor blocking agents are useful for treating lymphocyte-mediated immunological diseases, and more particularly, for inhibiting Th1 cell-mediated immune responses.
Current activities towards developing more effective treatment strategies for HIV/AIDS-related malignancies include: 1) targeting molecules in the angiogenesis and apoptotic pathways; 2) fortifying the immune system using immunomodulatory molecules, vaccines designed to increase the cell-mediated immune responses to viral antigens, and monoclonal antibodies to eliminate cancer cells; 3) targeting EBV or KSHV to disrupt the viral life cycle; 4) investigating low morbidity anal lesion ablation techniques, and 5) combining standard chemotherapy regimens with biologic therapies.
The first Phase I trial showed that Flunisyn(TM)generated statistically significant cell-mediated immune responses to the vaccine and was safe and well tolerated in vaccinated groups compared to placebo.
In mice, these fusions have been shown to elicit T cell-mediated immune responses that recognize appropriate influenza antigens.
14] While cell-mediated immune responses in immune-competent individuals often result in clearance and latency of HPV infection, decreased HPV-specific immunity in HIV infection can cause re-activation and active replication of HPV, resulting in clinically evident infection.