cellular transformation

cellular transformation

[¦sel·yə·lər ‚tranz·fər′mā·shən]
(cystallography)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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(2011), normal cells are exposed to Cr6+ that induces ROS generation and cellular transformation. Its production can be reduced by overexpression of antioxidants i.e., SOD1, SOD2, or CAT (Gupta et al., 2012).
The company's leading protein target is Lin28, an RMP that reduces the levels of Let-7, and has been shown to be an oncogene, promoting cellular transformation and tumorigenesis.
Their topics include the biology of the human papillomavirus life cycle, molecular mechanisms of E6 and E7 oncoproteins from human papilllomaviruses in cellular transformation, Epstein-Barr virus and the pathogenesis of lymphoma, the development of prophylactic and therapeutic vaccines for Epstein-Barr virus and its associated malignancies, Merkel cell polyomavirus: the new kind on the block, and Human adenovirus: tools to reveal mechanisms of cellular transformation and vector to treat human cancers.
In this study we examined an in vitro framework to identify a tolerated dosage of [As.sub.2][O.sub.3] that induces cellular transformation as an important prerequisite to epigenetic characterization.
Several studies have showed a major role of the E6 protein in the induction and maintenance of cellular transformation, acting mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins, culminating in the cervical cancer symptoms (Liu et al., 2009).
SMITHVILLE, Texas, February 13, 2013 -- Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
SMITH VILLE, Texas, February 13, 2013--Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
Washington, February 14 ( ANI ): Scientists have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
In this study on mice, metformin inhibited cellular transformation and selectively killed cancer stem cells in four genetically different types of breast cancer, and the combination of metformin and doxorubicin killed both cancer stem cells and non-stem cancer cells in culture (Cancer Res.
Written primarily for postdoctoral researchers, scientists and clinicians who need to enhance their knowledge of cellular transformation and oncogenesis, this book contains a detailed bibliography in each chapter for further research.
The vessel's upper deck houses a "living" sculpture of molded petroleum jelly undergoing cycles of stabilization and collapse (akin to the constant cellular transformation endured by whales as well as by human organisms); in one variation of this cycle, "Occidental Guests" (played by Barney and Bjork) visit the ship, participate in a tea ceremony, and transform themselves into whales.