cephalosporin


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cephalosporin

(sĕf'əlōspôr`ĭn), any of a group of more than 20 antibioticsantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 derived from species of fungi of the genus Cephalosporium and closely related chemically to penicillinpenicillin,
any of a group of chemically similar substances obtained from molds of the genus Penicillium that were the first antibiotic agents to be used successfully in the treatment of bacterial infections in humans.
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. Cephalosporins, e.g., cefaclor (Ceclor), act against both gram-positive and gram-negative bacteria (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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) by inhibiting bacterial cell wall synthesis. They are widely used to treat gonorrhea, meningitis, and staphylococcal and streptococcal infections in patients who cannot use penicillin. Overuse of cephalosporins has led to increased bacterial resistance to the drugs (see drug resistancedrug resistance,
condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs. Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to previously
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.)

cephalosporin

[‚sef·ə·lə′spȯr·ən]
(microbiology)
Any of a group of antibiotics produced by strains of the imperfect fungus Cephalosporium.
References in periodicals archive ?
Despite nucleic acid amplification test (NAAT) being negative for Chlamydia trachomatis, dual treatment with a cephalosporin plus either azithromycin or doxycycline is recommended by ACOG to prevent resistance to cephalosporins.
Sarika Jain et al1 carried out a study on 344 strains of Salmonella and resistance to 3rd generation cephalosporin was observed in 7(2%) strains of Salmonella Typhi.
Technavio's report, Global Cephalosporin Drugs Market 2015-2019, has been prepared based on an in-depth market analysis with inputs from industry experts.
This is a good time to mention that there is potential cephalosporin cross-sensitivity in patients with a true penicillin allergy (4% to 10% of cases) that has been observed predominantly with first-generation cephalosporins.
British meat and poultry organizations responded with a strongly-worded statement challenging the figures and pointing out that the industry no longer uses cephalosporins.
The number of avoidable deaths and the costs of health care potentially caused by third-generation cephalosporin use in food animals is staggering.
The development and spread of cephalosporin resistance in N.
She said her group has identified at least five foodborne outbreaks since 2001 linked to cephalosporin - resistant salmonella.
Therefore, the proportion of cephalosporin prescriptions affected by the new rule can't be easily discerned.
The FDA will prohibit certain uses of cephalosporins in specific food animals in an attempt to preserve the antibiotics effectiveness for treating human infections.