cephalosporin


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cephalosporin

(sĕf'əlōspôr`ĭn), any of a group of more than 20 antibioticsantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 derived from species of fungi of the genus Cephalosporium and closely related chemically to penicillinpenicillin,
any of a group of chemically similar substances obtained from molds of the genus Penicillium that were the first antibiotic agents to be used successfully in the treatment of bacterial infections in humans.
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. Cephalosporins, e.g., cefaclor (Ceclor), act against both gram-positive and gram-negative bacteria (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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) by inhibiting bacterial cell wall synthesis. They are widely used to treat gonorrhea, meningitis, and staphylococcal and streptococcal infections in patients who cannot use penicillin. Overuse of cephalosporins has led to increased bacterial resistance to the drugs (see drug resistancedrug resistance,
condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs. Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to previously
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.)

cephalosporin

[‚sef·ə·lə′spȯr·ən]
(microbiology)
Any of a group of antibiotics produced by strains of the imperfect fungus Cephalosporium.
References in periodicals archive ?
Nevertheless, the side effects of Cephalosporin Drugs and the development of drug-resistant bacterial strains restrict the growth of the market.
swollen hyphal fragments show high and medium productivity of cephalosporin (Bartoshevic et al., 1990).
Mortality in patients with SBP was related to severity of underlying liver cirrhosis but was not a consequence of cephalosporin resistance.
Cephalosporin and extended-spectrum macrolides represent logical options because of their demonstrated efficacy and safety.
Conversely, cephalosporins have a [beta]-lactam ring attached to a dihydrothiazine ring with two side chains.
In vivo efficacy of ceftaroline (PPI-0903), A new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model.
Answer B and C are incorrect because the patient is allergic to cephalosporin (ceftriaxone and Cefixime).
Resistance to the cephalosporin antibiotic cefixime, meanwhile, increased from 0.1% in 2006 to 1.4% in 2010 and 2011, fell to 0.4% in 2013, and increased to 0.8% in 2014.
The option left was to use either azithromycin or a third generation cephalosporin. The isolate from our patient was resistant to both of these antimicrobials as well.
All patients who were administered an antibiotic received a cephalosporin, clindamycin, or amoxicillin-clavulanate rather than penicillin or amoxicillin as the initial antibiotic therapy.
Cefazedone, a first-generation cephalosporin with activity against Gram-positive and Gram-negative bacteria, [sup][1],[2],[3] has been shown to be effective in the treatment of infections caused by sensitive bacteria.