Practice guideline update summary: botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia
, adult spasticity, and headache: report of the Guideline Development Subcommittee of the American Academy of Neurology.
Xeomin (incobotulinumtoxinA) is a prescription medicine that is injected into muscles or glands and used to treat adults with sialorrhea, increased muscle stiffness in the arm of adults with upper limb spasticity, the abnormal head position and neck pain that happens with cervical dystonia
in adults, and to treat abnormal spasm of the eyelids (blepharospasm) in adults who have had prior treatment with onabotulinumtoxinA (Botox).
is thought to be a result of systems-level disorder; therefore, vestibular pathologies may be associated due to proximity of vestibular nuclei and pathways.
In a recent paper, Antelmi and coworkers  found a reduced suppression of SEPs in cervical dystonia
at the ISI of 20 and 40 milliseconds, not confirmed in our study and in the study of Tamura and coworkers .
The site produces one of Ipsen's key strategic products, Dysport, which is used in the treatment of cerebral palsy, spasticity and cervical dystonia
Its main product is Dysport, which is approved for use in 80 countries worldwide and in therapeutic indications including cerebral palsy, spasticity and cervical dystonia
Botulinum neurotoxin types A (BTXA) and B (BTXB) are approvedbythe United States Food and DrugAdministration (FDA) including cervical dystonia
, severe primary axillary hyperhidrosis, strabismus, blepharospasm, hemifacial spasm, and glabellar wrinkles for BTXA and cervical dystonia
Fahn, "Current concepts on the clinical features, aetiology and management of idiopathic cervical dystonia
," Brain, vol.
Although parkinsonism [3, 4], tardive dyskinesia , tardive dystonia [5, 6], hemifacial dystonia , and oculogyric crisis  have been reported to be caused by clebopride, acute cervical dystonia
has not been observed in adults treated with this drug.
EDSS = 2 Patient 10 Cervical dystonia
+ pyramidal syndrome + vestibular syndrome + paraparesis.
Totally, 70 patients (cervical dystonia
, n = 30; blepharospasm, n = 30; oromandibular dystonia, n = 10) and 50 normal controls were included in the final analysis.