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A hormone found in the serum of humans and certain other animals during pregnancy; probably acting with progesterone and estrogen, it causes relaxation of pelvic ligaments in the guinea pig.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a hormone formed mainly in the ovaries that produces relaxation of the ligaments of the pubic symphysis of the pubic bones during pregnancy; as a result, the pelvis widens and normal childbirth is facilitated. Relaxin also characteristically inhibits the spontaneous contractions of the uterus.

Chemically relaxin is a polypeptide. Refined sow relaxin exhibits pronounced basic properties; it has molecular weight of about 6,500 and a structure of two subunits, consisting respectively of 22 and 28–31 amino-acid residues, joined by a disulfide bond. The primary structure has not been determined. The biosynthesis of either relaxin or the polypeptides that are closely related to it structurally is also possible in tissues found in the uterus and placenta.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.