channel protein

channel protein

[′chan·el ‚prō‚tēn]
(cell and molecular biology)
Protein forming an aqueous pore spanning the lipid bilayer of the cell membrane which when open allows certain solutes to traverse the membrane.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
In NMOSD, about 80% of patients have autoantibodies to a water channel protein called aquaporin-4.
Human male infertility caused by mutations in the CATSPER1 channel protein. Am J Hum Genet.
This abbreviation stands for epithelial sodium (Na) channel and describes a channel protein on the cell surface through which sodium ions stream into the cell's interior.
In the absence of the pacemaker channel protein HCN1, mice display congenital SAN dysfunction that was characterized by low heart rate, sinus arrhythmia, increased SAN conduction and recovery time, and recurrent sinus pauses [55].
Ketamine is an antagonist of the N-methyl-D-aspartate (NMDA) glutamate receptor and an ion channel protein. Amitriptyline serves primarily as a voltage-gated sodium channel antagonist, and lidocaine as a local anesthetic.
By using biolayer interferometry (BLI) technique, a novel methodology for detecting protein-protein or protein-small molecules interactions [48], we measured the kinetics change of binding between PI[P.sub.2] and purified hEAG1 channel protein and found that the kinetics of the BLI signal resembled those observed in the patch clamp measurements in the excised patches.
Using current in silico approaches, four such proteins were found and they are outer membrane channel protein tolC, outer membrane pore protein F, histidine kinase PhoQ, and histidine kinase envZ.
The deletion, concerned with an in-frame deletion of 5 amino acid residues in a highly evolutionarily conserved region within the cytoplasmic loop domain of the gap junction channel protein connexin 50 (Cx50), was in full cosegregation with the cataract phenotypes in the family but not found in 1100 control exomes.
London, United Kingdom, September 04, 2015 --(PR.com)-- Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results.
Aquaporins in Saccharomyces: characterization of a second functional water channel protein. Proc.