Studying kinetic of metal sorption is quite significant in SPE because the effectiveness of the sorption process of analytes by the chelator
from aqueous solutions governed by the sorption dynamics .The sorption of the examined metal ions carried out with portions of 50 mg of resins added to 50 ml of a metal ion solution containing 5 mg/L and agitated mechanically for different time intervals (2, 5, 10, 15, 30and 60 min).
Atomic absorption spectrometry and scanning electron microscopy evaluation of concentration of calcium ions and smear layer removal with root canal chelators
. J Endod 2009; 35: 727-30.
can be used in severe poisoning like dimercaprol, D-penicillamine, British Anti-Lewisite (BAL), Ethylene Diamine Tetra Acetate (EDTA).
It thus makes sense to 'cleanse' the digestive tract prior to chelation, because a properly prepared intestinal tract will allow the oral chelator
to pass relatively unbound through the mucous membranes into the blood stream from where it is transported to organ systems in need of detoxification.
A class of iron chelators
with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics.
The results point that intracellular zinc levels in cells treated with 25 [micro]M TPEN decreased compared with the control cells (cells with no chelator
, Figure 1(c)), whereas cells treated with 5 [micro]M TPEN showed no significant changes in the zinc levels.
The results obtained showed that the hexane extract is a good chelator
. This activity was evaluated by the chelation tests of iron, zinc and copper prove that the extract of the hexane Phragmites australis possess very advantageous chelating properties compared to standard chelator
However, most synthetic chelators
like EDTA and EDDS form complexes with metals which have high stability and contaminate the groundwater (Zeremski-Skoric et al., 2010).
The use of iron chelators
is an accepted method of removing excess iron from these patients.
Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator
, in comparision to deferoxamine in thalassemia patients with transfusional iron overload.
All the difficulties in the administration of standard iron chelators
called for attempts to find out new orally active iron chelators
The side effects or reasons leading to cessation of chelator
therapy (deferasirox) or necessitating a change in initial therapy were studied.