Among the various synthetic methods for metal chelators
, the covalent chemical attachment of chelating agents onto the surface of porous solid substrates; 'post synthesis modification', is a favorable approach due to the availability of wide variety of high surface area and stable materials.
Atomic absorption spectrometry and scanning electron microscopy evaluation of concentration of calcium ions and smear layer removal with root canal chelators
. J Endod 2009; 35: 727-30.
Robinson et al., "Comparison of DOTA and NODAGA as chelators
for 64Cu-labeled immunoconjugates," Nuclear Medicine and Biology, vol.
If the patient develops acute kidney injury, the use of these chelators
can cause more toxicity.
DMSA or Meso-2,3-dirnercaptosuccinic acid has been used as a heavy metal chelator
since the 1950s, and was extensively researched in the People's Republic of China, Japan, and Russia before it spread to Europe and the USA.
induce apoptosis in proliferating cells.
The EDTA (standard chelator
) produced to a significant (p [less than or equal to] 0.01) effect (97 %) compared to the control.
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) is a membrane-permeable hexadentate compound which chelates metal ions such as [Cu.sup.2+], [Zn.sup.2+], and [Fe.sup.2+] [1,2], but this intracellular chelator
has shown a high affinity for zinc [3-5].
, organic or inorganic agents are being widely used for metals mobilization to rehabilitate the metal contaminated soils by plants (Madrid et al., 2003; Chen et al., 2014), they form the water soluble complexes with metal ions and desorb them from various soil components (Sun, 2009).
The use of iron chelators
is an accepted method of removing excess iron from these patients.
All the difficulties in the administration of standard iron chelators
called for attempts to find out new orally active iron chelators
Differential modulation of synaptic transmission by calcium chelators
in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging.