The widespread use and exposure of chemical carcinogens
is one of the major causes of skin diseases (Harper 2004; Housman et al., 2003).
Preconceptional exposures during sperm or oocyte maturation have led to transgenerational carcinogenesis for several types of radiation and a variety of chemical carcinogens
(reviewed in Tomatis 1989).
In one case, CLA administered just during the 5 weeks when a rat's mammary tissue was maturing offered strong protection against the development of tumors later, when the researchers exposed the animal to one of two potent chemical carcinogens
. Animals whose diets contained 1 percent CLA by weight -- the equivalent of about 30 times the amount eaten by the average 155-pound human -- developed just two-thirds as many mammary cancers as rats given no CLA.
"This is the strongest liver cancer effect that I have seen with a chemical carcinogen
Models for studying mammary carcinogenesis have been developed in Sprague-Dawley rats, with the chemical carcinogen
DMBA (15-17), which induced mammary carcinomas in 100% of the animals with a latency period of 86 days (15).
The twenty-five selections that make up the main body of the text are devoted to the measurements of toxicants and toxicity, food chemical carcinogens
, absorption of food toxicants, an overview of food allergies in children and adults, and a wide variety of other related subjects.
"It is certainly very inappropriate to suggest that any adverse effect of bacon and sausages on the risk of bowel cancer is comparable to the dangers of tobacco smoke, which is loaded with known chemical carcinogens
and increases the risk of lung cancer in cigarette smokers by around 20-fold," Johnson (http://www.bbc.com/news/health-346156
They found no signs of hybrid hepatocytes in any of the tumors, leading the researchers to conclude that these cells don't contribute to liver cancer caused by obesity-induced hepatitis or chemical carcinogens
Exposure to tobacco-related chemical carcinogens
could provide direct damaging effects on the cellular DNA in the human oral cavity.
As an example, polycyclic aromatic hydrocarbons (PAH) are chemical carcinogens
that belong to the group of xenobiotics which are able to initiate carcinogenesis in cells of various human tissues.
In addition to chemical carcinogens
, the panel calls for increased monitoring of the effects of cell phones and wireless technology and of medical radiation.
Prior to 1972, it was not yet clear that the electro-philicity of some chemical carcinogens
had a necessary role in the potential mutagenic activity of such compounds or even that DNA, as opposed to protein, was the ultimate target of carcinogens (Miller 1970).