chemokine

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Related to chemokine: cytokine, interleukin, Chemokine receptor

chemokine

[′kē·mə‚kīn]

(cell and molecular biology)

A small (7-14 kilodaltons of soluble protein) chemoattractant cytokine produced by cells and tissues at the beginning of an immune system response to infection, allergen, injury, and so forth that controls the nature and magnitude of immune cell infiltration and inflammation at the affected site.

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CCR5

References in periodicals archive ?

- The report reviews C-X-C Chemokine Receptor Type 2 (CDw128b or GRO/MGSA Receptor or High Affinity Interleukin 8 Receptor B or IL8 Receptor Type 2 or CD182 or CXCR2) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

C-X-C Chemokine Receptor Type 2 Pipeline Review, H1 2019

CCL, CC-motif chemokine ligand; CXCL, CXC-motif chemokine ligand; G-CSF, granulocyte colony-stimulating factor; IFN-y, interferon y; IL, interleukin; MMP, matrix metalloproteinase; sICAM-1, soluble intercellular adhesion molecule 1; VEGF-A, vascular endothelial growth factor A.

Peripheral Plasma and Semen Cytokine Response to Zika Virus in Humans

WHIM syndrome is a primary immunodeficiency disorder characterized by panleukopenia and caused by autosomal dominant gain-of-function mutations in CXC chemokine receptor 4 (CXCR4).

Plerixafor produced dramatic responses in severe WHIM syndrome

The CC-type ligands CCL17, CCL21, and CCL24 are considered dual chemokine and homeostatic chemokines, respectively.

Characterization of Dual and Homeostatic Chemokine Expression and Response to Bacterial Infection in Large Yellow Croaker, Larimichthys crocea

While our study focused on eotaxin-2, this chemokine acts in close interaction with a large number of additional mediators, which has not been investigated in the present cohort.

Elevated Levels of Eotaxin-2 in Serum of Fibromyalgia Patients

Nonparametric Kruskal-Wallis followed by Mann-Whitney U tests, when appropriate, were performed to determine the statistical significance for the difference of cytokine and chemokine concentrations between the BMS-COPD, BMS-CONTROL, and TS-BMS-CONTROL or TS-COPD, TS-CONTROL, and TS-BMS-CONTROL groups.

Putative Systemic Biomarkers of Biomass Smoke-Induced Chronic Obstructive Pulmonary Disease among Women in a Rural South Indian Population

The recruitment of activated lymphocytes to mucosal surfaces is strictly controlled, requiring the expression of specific chemokine receptors and adhesion molecules.

Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants

KEYWORDS: Atypical chemokine receptor 1, Hepatitis C virus, Liver damage, Liver fibrosis, Polymorphism, Serum liver related markers.

Atypical Chemokine Receptor 1 polymorphism cannot be used as an indicator of liver fibrosis progression in Hepatitis C virus positive patients

Inhibition of phosphodiesterase 4 suppresses lipopolysaccharide-induced CC chemokine ligand 3 production in mouse macrophages

Phosphodiesterase 4B is essential for lipopolysaccharide-induced CC chemokine ligand 3 production in mouse macrophages

Although the molecular mechanisms regulating HIV chemokine receptors in the cervix are unclear, inflammatory prostaglandins derived by metabolism of arachidonic acid by cyclo-oxygenase enzymes (COX-1 and COX-2)[9] have been shown to regulate HIV chemokine expression in uterine epithelial cells in the female genital tract.

Regulation of HIV receptor expression in cervical epithelial cells by gram-negative bacterial lipopolysaccharide

The papers range from 'Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors; to The Chemokine System in Innate Immunity; to Inflammation and the Blood Microvascular System; to Approaching the Next Revolution?