chemoprevention

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chemoprevention

[¦kē·mō·pri¦ven·shən]

(medicine)

Prevention of illness through pharmaceutical means; for example, use of drugs to arrest or reverse development of premalignant neoplasia.

References in periodicals archive ?

This protection with relatively short use and its fairly stable magnitude thereafter bode well for using bisphosphonates for chemoprevention, according to Dr.

Bisphosphonate use may cut colon cancer

Advanced adenomas--large, intramucosal or invasive adenomas containing histologic features associated with conversion to colorectal cancer--were seen in nine (9.3%) patients in the placebo group and one patient receiving combination chemoprevention. More than one adenoma was found in 15 patients receiving placebo versus just 1 patient in the chemoprevention arm.

Old drug combo prevents colorectal adenomas

This finding is particularly relevant because multiple large, long-term, multicenter phase III clinical trials of aromatase inhibitors for breast cancer chemoprevention are getting underway this year.

Concerns crop up about aromatase inhibitors. (Musculoskeletal Problems, Fractures)

A number of agents are being investigated for the chemoprevention of skin cancers.

Skin Ca chemoprevention under investigation

Since the start of the randomized Aspirin Esomeprazole Chemoprevention Trial (AspECT) in September 2005, 1,192 (83%) of the 1,436 patients have remained on their medication, and just 33 adverse events have been reported, said the study's lead investigator Dr.

Aspirin and Esomeprazole appear safe for Barrett's

He and his colleagues plan to launch a prospective prostate cancer prevention trial using risk alleles and family history to guide chemoprevention with finasteride.

Genes plus family history show prostate Ca risk

Cancer chemoprevention; v.2: Strategies for cancer chemoprevention.

Cancer chemoprevention; v.2: Strategies for cancer chemoprevention. (CD-ROM included)

Preventive Services Task Force "strongly" recommended last month that "clinicians discuss aspirin chemoprevention with adults who are at increased risk of coronary heart disease."

Aspirin gets the nod for primary cardiac prevention: Postmenopausal women, diabetics targeted. (U.S. Preventive Services Task Force)

Induction of phase II genes may contribute to primary chemoprevention of colon cancer by apple polyphenols.

GSTT2, a phase ii gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage

Digoxin could conceivably find a role for chemoprevention in selected high-risk men, or perhaps in the treatment of prostate cancer, but its potent cardiovascular effects make it poorly suited for use in broad-scale chemoprevention, she said.

Prostate cancer risk lower in digoxin users

Perhaps one man's binge drinking is another man's chemoprevention. The micronutrient xanthohumol, a flavonoid compound found only in hops, shows promise in cancer prevention, according to a report from the Linus Pauling Institute at Oregon State University in Corvallis.

'What shall I do now? What shall I do?'

white women aged 35-49 years who have any risk factors for breast cancer would derive substantial net benefit from 5 years of tamoxifen for chemoprevention.