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Use of drugs to prevent the development of infectious diseases.



a method of preventing diseases—primarily infectious diseases—by using chemical agents. Primary chemoprophylaxis is the administering of chemical agents to healthy persons likely to become infected in epidemic focuses of cholera or plague and in regions where malaria is prevalent. Chemical agents may also be administered to individuals who come into regular contact with tuberculous patients and to persons engaging in casual sexual relations. Chemoprophylaxis helps to prevent infectious diseases and complications in surgical patients likely to experience suppuration and in patients with low immunity (for example, the administration of antibiotics to those undergoing treatment with cytostatic agents or to debilitated influenza patients to prevent inflammation of the lungs).

Secondary chemoprophylaxis is the use of chemical agents to prevent recurrences of neoplasms (for example, in leukemia or after radical excision of a tumor) and rejection of organs and tissues after transplantation.

References in periodicals archive ?
Despite its widespread use as a UTI chemoprophylactic agent, the resistance percentage of this drug remains very low (3%) (Fig.
Mefloquine was removed as a primary chemoprophylactic medication primarily due to concern for the ability to adequately screen all service members for behavioral health contraindications.
Hematologic examination of cattle in Pakistan during haemoparasitic infections and chemoprophylactic activity of imidocarb, diminazene and oxytetracycline against babesiosis.
Chemoprophylactic effects of azithromycin against Rhodococcus equi - induced pneumonia among foals at equine breeding farms with endemic infrctions.
In the process, they focused on harms as well as benefits associated with use of these chemoprophylactic agents.
The chemoprophylactic effect appears not to be the same for all subgroups of contacts.
Families traveling to areas with increased risk of acquiring malaria should be protected against malaria by reducing exposure to mosquitoes and using appropriate chemoprophylactic regimens, including chloroquine, atovaquone/proguanil, mefloquine, or doxycycline (CDC, 2007b; Chen et al.
Please note that this table does not include all possible interactions with malaria chemoprophylactic drugs.
Radley D, Brown C, Burridge M, Cunningham M, Kirimi I, Purnel R, Young A (1975) Chemoprophylactic immunisation of cattle against Theileria parva (Muguga) and five Theileria strains.
Furthermore, we observed from our study that most pregnant women did not commence the intake of chemoprophylactic drugs, including haematinics and folate, until they commenced to attend antenatal care clinics.
WASHINGTON -- Long-term travelers to countries with high risk for malaria should use personal protective measures and chemoprophylactic regimens based on the risk factors they are likely to encounter, Patricia Schlagenhauf-Lawlor, Ph.