Caption: Figure 4: The connections of leukocyte cell-derived chemotaxin
Treatment of neutrophils with the chemotaxin
, formylmethionylleucylphenylanaline, leads to a translocation of n-SMase to plasma membranes where it is involved in the spreading and the extension of pseudopods.
Hugli, "C3a is a chemotaxin
for human eosinophils but not for neutrophils.
For example, leukocyte cell derived chemotaxin
1, also known as chondromodulin-I, inhibits angiogenesis in avascular tissues such as cartilage and avascular compartments in the eye.
Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin
. J Clin Invest 1991;88:1362-9.
However, an age-associated lack of neutrophil chemokinetic accuracy in response to the chemotaxin
fMLP has been reported , which suggests that the mechanism is probably related to age-induced compromise of specific cellular mechanisms, rather than activation.
Circulating and tissue levels of the neutrophil chemotaxin
interleukin-8 are elevated in severe acute alcoholic hepatitis, and tissue levels correlate with neutrophil infiltration.
Interleukin 8 (IL-8) is a potent neutrophil activator and chemotaxin
that is often used as a biological marker of environmentally induced pulmonary inflammation (Kunkel et al.