chikungunya


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chikungunya

(chĭkən-go͞on`yä), viral disease transmitted by the bite of an infected female Aedes mosquito. Symptoms appear after an incubation period of four to eight days and include sudden high fever, severe joint and muscle pain, and often headache, nausea, fatigue, and rash. The virus, of genus Alphavirus, occurs mostly in Africa, Asia, and the Indian subcontinent, but in recent decades has been found in Europe and the Americas. Though the disease is seldom fatal and symptoms generally subside after a few days, there is no cure for chikungunya, and it can cause long-term joint pain and other complications. Non-aspirin medications that reduce fever and relieve pain may help alleviate symptoms. Infection may be avoid by preventing mosquito bites with insect repellents and protective clothing and by removing water-filled breeding sites. The disease is sometimes misdiagnosed as dengue feverdengue fever
, acute infectious disease caused by four closely related viruses and transmitted by the bite of the female Aedes mosquito; it is also known as breakbone fever and bone-crusher disease.
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, especially in areas where dengue is common. The virus was first identified in 1953, in Tanzania (then Tanganyika). Since 2000 there have been epidemics in several countries in SE Asia as well as islands in the Indian Ocean and the S Pacific. In 2007 the first outbreak in Europe occurred in NE Italy. The first outbreak in the Americas began in the Caribbean in 2013, and the first domestically acquired cases occurring in the United States were recorded in S Florida in 2014.
References in periodicals archive ?
Chikungunya virus is spread by mosquitoes and causes severe joint and muscle pain.
The Centers for Disease Control (CDC) said Sunday it has issued the Level 1 travel advisory for chikungunya infection for the first time, warning against all non-essential travel to Myanmar, Maldives, Thailand and India -- countries where the virus was imported into Taiwan since July.
Twenty-five chikungunya fever cases have been confirmed this year, including the first indigenous case ever reported in Taiwan.
With support from the European Union's (EU's) Horizon 2020 programme, CEPI will provide Valneva up to US$23.4 million for vaccine manufacturing and late-stage clinical development of a single-dose, live-attenuated vaccine (VLA1553) against Chikungunya. In line with CEPI's committment to equitable access, the funding will underwrite a partnership effort to accelerate regulatory approval of Valneva's single-dose Chikungunya vaccine for use in regions where outbreaks occur and support WHO prequalification to facilitate broader access in lower and middle income countries.
Mentri Besar Datuk Seri Mukhriz Mahathir said the incidence of chikungunya was quite worrying even though it was still under control.
He added Chikungunya is a viral disease caused by Chikungunya Virus (CHKV) and transmitted by Aedes mosquitoes to humans.
Chikungunya virus infection represents a significant unmet medical need having no vaccine or treatment available despite its emergence as a global threat because of the highly debilitating nature of the associated disease and unprecedented magnitude of its spread.1 We look forward to completing the data set analysis and finalizing our development plan, which could allow for initiation of a pivotal trial next year.
Patients who presented with symptoms suggestive of Chikungunya Fever were tested for CHIKV IgM antibodies, and those who tested positive (88) were then included in the study.
Respiratory symptoms are not present in chikungunya. (5)
The CHIKV genotyping details were obtained using the Dengue, Zika & Chikungunya Viruses Typing Tool (v.
DENV and CHIKV are often found co-circulating during outbreaks and have an overlapping clinical presentation; thus, misdiagnosis and underreporting of chikungunya infection in dengue-endemic areas is common (4).
Chikungunya is an arboviral disease caused by the chikungunya virus--an alphavirus --and is largely transmitted by the Aedes aegypti and Aedes albopictus mosquito species.