chimerism


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Related to chimerism: blood chimerism

chimerism

[′kī·mə‚riz·əm]
(biology)
The admixture of cell populations from more than one zygote.
References in periodicals archive ?
Although our assessment used qPCR methodology, the concept of targeting CND polymorphisms for chimerism analysis is translatable to other plat forms, such as digital PCR and next generation sequencing.
Chimerism analysis using polymerase chain reaction (PCR)-based amplification of short tandem repeat (STR) markers has grown to be the most widely used tool for analyzing stem cell engraftment over fluorescent/ns/fu hybridization (FISH) and other cytological methods.
The colonial ascidian Botryllus schlosseri (Pallas, 1766) is an excellent model for the study of allorecognition and chimerism.
This unexpected form of chimerism indicates that the heart possesses a population of cardiac stem cells and implies that it has the capacity replace mature cells destroyed by heart attack or disease, wrote Anversa and coauthors in the January 3 issue of the New England Journal of Medicine.
The recipient subjects developed durable mixed chimerism, where the resulting immune system was a mixture of donor and recipient cells.
Extensive chimerism in liver transplants: vascular endothelium, bile duct epithelium, and hepatocytes.
For the HSCT patients, fluorescence in situ hybridization and short tandem repeat DNA analyses for peripheral blood chimerism were performed as previously described (15).
One year after transplant, she presented with isolated leukemic infiltrates in the left pleura, while her marrow showed no sign of the disease with a 100% donor chimerism.
By inducing mixed chimerism, transplant surgeons at Harvard Medical School in Boston, MA have been able to discontinue immunosuppressive therapy after kidney transplantation.
While the presence of CB001 was detected in some patients at earlier time points, chimerism from CB001 was not detected at 21-28 days post transplant.