chimerism


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Related to chimerism: blood chimerism

chimerism

[′kī·mə‚riz·əm]
(biology)
The admixture of cell populations from more than one zygote.
References in periodicals archive ?
Figure 8 contains the corresponding result table of the percent donor at each locus, total percent donor chimerism, and quality metrics.
Consequently, we cannot rule out the potential contributions of chimerism to the genetic disparities in these corals, and these individuals were not included in assessments of somatic mutations.
Mosaicism, gene mutations and chimerism have been shown as primary causes of development of ovotesticular DSD.
The detection of genomic chimerism, [greater than or equal to] 2 cell populations from differing genetic origins within an individual, has diverse clinical applications including identifying fetal microchimerism in autoimmune diseases (1), graft injury and transplant rejection (2, 3), and the clinical management of allogeneic hematopoietic stem cell transplantation (HSCT) [2] patients.
Chimerism concerns encompass crossing inviolable species borders.
The Accel-NGS Unique Dual Indexing Kits are an essential addition to NGS workflows, as current tools can suffer from demultiplexing problems caused by index read errors, PCR-induced chimerism associated with multiplexed hybridisation capture workflows, and index hopping on patterned flow cells, it said.
Chimerism studies at day +30 after transplantation indicated 25% donor lymphoid cell engraftment on peripheral blood, and bone marrow (BM) biopsy showed a cellularity of 5%.
Facilities like viral assay, HLA typing, donor specific antibody screen, chimerism, fluorescent in situ hybridization, and drug levels can be outsourced to central laboratory.
The chimerism in MSCs was analyzed by the STR-PCR method (polymerase chain reaction with a panel of primers for the loci of short tandem repeats).
She showed no sign of GVHD at any time after the transplantation, and she achieved full donor chimerism.
A repeat bone marrow biopsy following transplant did not show any evidence of multiple myeloma, and there was 91% donor chimerism. Immunosuppression leads to numerous episodes of pneumonia, and his course was complicated by renal insufficiency and acute grade III graft versus host disease, which was successfully treated with a steroid taper.