Chloral


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Related to Chloral: chloral hydrate

chloral

[′klȯr·əl]
(organic chemistry)
CCl3CHO A colorless, oily liquid soluble in water; used industrially to prepare DDT; a hypnotic. Also known as trichloroacetic aldehyde; trichloroethanal.

Chloral

 

trichloroacetic aldehyde, CCl3CHO; a colorless liquid, with a pungent odor and a boiling point of 97.75°C. Chloral interacts energetically with water, alcohol, and ammonia to form well-crystallized products (see). Chloral is obtained by the chlorination of ethyl alcohol. It is used in the production of insecticides, such as khlorofos and 4,4’-dichlordiphenyltrichloroethane (DDT), as well as in the production of herbicides, trichloroacetic acid, and chloroform.

References in periodicals archive ?
Pediatric chloral hydrate poisonings and death following outpatient procedural sedation.
Cocaine-induced Fos expression in rat striatum is blocked by chloral hydrate or urethane.
Immunofluorescent Staining: For this procedure, animals were perfused transcardially with 4% paraformaldehyde solution under high dose chloral hydrate anesthesia and following cryoprotection in 30% sucrose solution; brains were cut in the coronal plane at 20 [micro]m using a cryostat (Cryostat-Leica CM 1100).
At 48 h after MCAO, the rats (n = 6 per group) were anesthetized with chloral hydrate (10%, stored in 4[degrees]C refrigerator) and decapitated.
After assessment of the neurological defect score, rats (n = 5 per group) were anesthetized with 10% chloral hydrate (3ml/kg BW, i.p.) and perfused transcardially with ice PBS followed by 4% PFA (paraformaldehyde in PBS, pH = 7.4).
All mice were sacrificed by decapitation under deep anesthesia (3% chloral hydrate, 10 mL/kg body weight, i.p.; SigmaAldrich, St.
Among 25 included studies, one study used ether cotton balls to induce anesthesia [33], two studies used urethane [17, 26], eleven studies used chloral hydrate [16, 23, 27, 28, 30, 32, 35-38, 40], four studies used pentobarbital sodium [18, 20, 31, 39], three studies did not report anesthesia [24, 29, 34], and the remaining four studies did not report the method of executing the animals [19, 21, 22, 25].
Chloral hydrate (batch number: Q/12HB 4218-2010) was purchased from Tianjin Kermel Chemical Reagent Co., Ltd.
Naive rats were anesthetized with an intraperitoneal injection of 10% chloral hydrate (0.3 ml/100 g).
The records contain little information on physical treatment except for the use of such general sedatives as potassium bromide or chloral hydrate.