"We want to find a safe and effective treatment for women with cholestasis
of pregnancy so that we can prevent stillbirths in this condition.
Lumbroso et al (3) presented a case series of 113 patients with MAS, six of whom had evidence of cholestasis
. Specific G-protein mutations have been identified in two case reports of patients with cholestasis
and MAS (4,5).
Additionally, soy lipids impair biliary secretion, resulting in cholestasis
and liver failure (Rollins et al, 2013).
and hepatomegaly exist in all patients, a mild elevation of ALT, AST and ALP levels in association with a normal GGT level are particularly seen in this syndrome (1-4).
(3) reported the causes of cholestasis
that was misdiagnosed as BA and, they found that approximately 6.8% of the infants were misdiagnosed as BA and were diagnosed PFIC3, idiopathic neonatal hepatitis, cytomegalovirus hepatitis, Alagille syndrome, and CHF on the follow-up.
Chi square was used to test for significance in the prevalence of biliary atresia in malesvs females with neonatal cholestasis
as well as between males and females in comparable age related groups.
This could have indicated hepatitis, cholestasis
, or some another critical condition such as biliary atresia, giant cell neonatal hepatitis, toxoplasmosis, and intra or extra hepatic obstruction.
Keywords: Familial intrahepatic cholestasis
, Biliary diversion, Pruritus.
Therefore, the presence of vitamin B12 deficiency in cases with cholestasis
or hyperbilirubinemia may show an association.
. Bile plays a role in the human body not only for the emulsification and digestion of fatty substances, but also regulates many critical facets of physiology including glucose and cholesterol metabolism as well as thyroid hormone activation.
In a Kawasaki disease series with 35 cases, reported from Turkey, acute cholestasis
was not reported as a baseline finding .
Furthermore, other important liver grafts refusal was evaluated by histological analysis with severe steatosis, cholestasis
, and fibrosis.