The toxic effect of bile acids is well documented [21, 29, 30] and accumulation in the liver is one of the main factors associated with cholestasis
Lipoprotein X in a patient with cholestasis
11,52) More formal analysis has additionally shown that the degree of necrosis, fibrosis stage, microvesicular steatosis, panacinar steatosis, cholangiolar cholestasis
, ductular reaction, neutrophils, and portal venopathy were all associated with a higher degree of severity of DILI.
Alkaline phosphatase levels typically are high in patients with cholestasis
, but the zinc deficiency disorder in these infants resulted in low alkaline phosphatase levels.
Inhibition of BSEP and MRP2 by miroestrol and deoxymiroestrol might lead to hepatic bile acid retention and, subsequently, result in intrahepatic cholestasis
(Yu et at.
Before she gave birth she developed obstetric cholestasis
, a potentially lethal condition that had also hit her pregnancy with Isobel.
Thus, a patient with liver dysfunction manifesting with cholestasis
of infancy may be at increased risk of developing hypoglycemia.
Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
Ali has a birth defect, which is called Familial Cholestasis
Fifty year-old female patient with a five-year history of autoimmune hepatitis and secondary cholestasis
managed by gastroenterology and dermatology.
Speaking about drugs causing cholestasis
he mentioned Rifampicin, tetracycline, TCAs, Amoxicillin Clavulates etc.
There is an uncommon condition that can occur in the last trimester of pregnancy called obstetric cholestasis