cholinergic

(redirected from cholinergic receptors)
Also found in: Dictionary, Thesaurus, Medical.
Related to cholinergic receptors: Nicotinic receptors

cholinergic

[¦kō·lə¦nər·jik]
(physiology)
Liberating, activated by, or resembling the physiologic action of acetylcholine.
References in periodicals archive ?
The selective muscarinic cholinergic receptor antagonists used were: pirenzepine (Ml receptor; 10 and 100 nM); methoctramine (M2 receptor; 1 and 10 AM); N-(2-chloroethyl)-4-piperidinyl diphenylacetate N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP; M3 receptor; 10 and 100 nM); and tropicamide (M4 receptor, 1 and 10 [micro]M).
Tobacco and alcohol use may be related at least partially because both nicotine and alcohol affect brain nicotinic cholinergic receptors (Collins 1990; Little 2000).
Karuna is a clinical-stage drug development company focused on targeting muscarinic cholinergic receptors for the treatment of neuropsychiatric disorders including psychosis in schizophrenia, psychosis in Alzheimer's disease, and pain.
The drug's action on central muscarinic cholinergic receptors could be responsible for its effect on mood.
Antibodies to beta adrenergic and muscarinic cholinergic receptors in patients with chronic fatigue syndrome.
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.
Anticholinergics inhibit muscarinic cholinergic receptors. They have no role in treating nasal congestion.
- US-based drug development company Karuna Pharmaceuticals, Inc, which is focused on targeting muscarinic cholinergic receptors for the treatment of neuropsychiatric disorders marked by psychosis and cognitive impairment, has initiated a Phase 2 study evaluating the efficacy and safety of its lead product candidate, KarXT (Karuna-Xanomeline-Trospium), for the treatment of psychosis in schizophrenia, the company said.
[sup][27],[28] In addition, an increase of cholinergic receptors is one of the most significant features of narcolepsy, which might comprise an adaptive response to the malfunction of the secretion of acetylcholine and dopamine.
(The autonomic nervous system is regulated by adrenergic and cholinergic receptors in the sympathetic and parasympathetic nervous systems respectively.