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Hives or nettle rash; a skin condition characterized by the appearance of intensely itching wheals or welts with elevated, usually white centers and a surrounding area of erythema. Also known as hives.



nettle rash, an allergic reaction characterized by the sudden and rapid appearance on the skin (sometimes also on the laryngeal mucosa) of intensely itching wheals.

Urticaria is often caused by the sting of the nettle and certain other plants. Insect bites, temperature, and chemical agents are also among its causes. Other factors include parasitic worms, chronic constipation, liver and kidney diseases, and allergic sensitivity to some foods (for example, strawberries, citrus fruits, eggs, mushrooms, preserves, certain fish, pork, and chocolate). Urticaria is sometimes caused by hypersensitivity to drugs (especially to those of chemical origin). The rash associated with the condition is a manifestation of the inflammatory reaction and edema of the skin that result from a sudden increase in the permeability of the capillaries in the area. This results from the liberation of histamine from the mast cells of the skin by allergic alteration. Urticaria usually disappears without a trace within a few hours, although it sometimes recurs. It is treated by purgation (by enemas, laxatives), special diet (mostly milk and vegetables, with limited salt intake), and desensitizing and anti-histaminic agents.


Pavlov, S. T. Kozhnye i venericheskie bolezni, 2nd ed. Moscow, 1969.


References in periodicals archive ?
Patients with dermographism and delayed pressure urticaria were more sensitive to omalizumab (13 out of 15 patients showed a complete response) than patients with cold and cholinergic urticaria (3/6 and 6/8 respectively showed a complete response).
Hydroxyzine is especially effective for the treatment of cholinergic urticaria.
researchers' task of identifying the syndrome and its cases, symptoms are difficult to reproduce in laboratory experiments even when victims are challenged with exercise programs identical to those that precipitated episodes, and symptoms are similar to other allergic reactions that occur during exercise like cholinergic urticaria and exercise-induced asthma.