Because bradycardia is a relatively common occurrence in older patients after using cholinesterase inhibitors
[6,7], Holter ECG parameters such as mean heart rate (HR), the lowest HR, and the longest RR were determined.
Kurz A, Van Baelen B: Ginkgo biloba compared with cholinesterase inhibitors
in the treatment of dementia: a review based on meta-analyses by the Cochrane collaboration.
Bradycardia is a contraindication for all cholinesterase inhibitors
The most common pesticide exposures across all age groups were cholinesterase inhibitors
(25.3%), anticoagulant rodenticides (20.5%) and pyrethroids (14.4%).
(2000) that CPF is more than a cholinesterase inhibitor
. Crumpton et al.
The newest cholinesterase inhibitor
, rivastigmine, has not been compared head to head with donepezil, the most common treatment.
Data source: Data from 385 patients in the nonrandomized, multicenter Swedish Alzheimer Treatment Study (SATS), launched to evaluate the long-term effectiveness of cholinesterase inhibitor
treatment in a routine clinical setting.
Moreover, costs related to drug-combination treatment are falling: Memantine is expected to be available as a generic drug within a few years, and galantamine, a cholinesterase inhibitor
, is already available in generic form.
The study, published in the July/September issue of Alzheimer's Disease and Associated Disorders, included 382 patients, mean age 73,144 of whom received no drug treatment, 122 who were treated with a cholinesterase inhibitor
(CI), such as donepezil (Aricept), and 116 who received both a CI and memantine (Namenda).
Recent studies, however, have failed to show a clinically or statistically significant benefit from cholinesterase inhibitor
augmentation in schizophrenia (Table 2).
Long-term cholinesterase inhibitor
therapy for Alzheimer's disease: practical considerations for the primary care physician.
The first controlled study assessing workers who suffered acute poisoning from cholinesterase inhibitor
compounds and/or organochlorides was reported by Savage et al.