chondrogenesis


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chondrogenesis

[¦kän·drō·jə′nē·səs]
(embryology)
The development of cartilage.
References in periodicals archive ?
Citation: Melika Sarem et al., Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis. Stem Cell Research & Therapy, 2019; 10 (1) DOI: 10.1186/s13287-018-1103-y
Non-conventional chondrosarcomas and chondrogenesis. Histopathology.
The In vitro study investigated that mutant GDF5 was unable to provoke chondrogenesis to the same degree as its wild type counterpart.
A promising hydrogel for the biofabrication of such implants is gelatin methacryloyl (gelMA) with gellan gum, which can be UV cross-linked, retains its shape during crosslinking and culture, and was demonstrated to support chondrogenesis of embedded chondrocytes (Mouser et al., 2016b).
Also, Absence or low expression of Endoline (CD105) correlated with a subgroup of adipose-derived cells with increased osteogenic gene expression [36, 48], while the selection of CD105 positive (CD105+) MSCs favors chondrogenesis [49].
MSC chondrogenesis was also enhanced on cellulose derived glycosaminoglycan mimetic scaffolds by Huang et al., given that glycosaminoglycans provide signaling cues in native cartilage tissue [19].
Chondrogenesis was confirmed by immunohistochemistry.
These procedures are supposed to stimulate chondrogenesis coupled to the formation of fibrocartilage and/or hyaline cartilage.
[1,13] It is also necessary for the various chondrocyte nutrition states, including cell proliferation, re-differentiation, and chondrogenesis. [14] In other words, Mg serves as a chondroprotective element by increasing the cell proliferation, protein expression, and growth factor efficacy.
The transition from chondrogenesis to osteogenesis occurs in the erosive zone, where the chondrocytes begin to synthesize alkaline phosphatase, and concomitantly, the cartilaginous matrix undergoes calcification (Meikle, 2007).
Human mesenchymal stem cells (hMSCs) can undergo chondrogenesis when exposed to transforming growth factor-[beta] (TGF[beta]) in vitro.