Chondrosarcoma

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chondrosarcoma

[¦kän·drō·sär′kō·mə]
(medicine)
A malignant tumor of cartilage.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Chondrosarcoma

 

a malignant tumor of cartilage tissue, sometimes accompanied by mucous degeneration; a type of sarcoma. Chondrosarcomas most often occur in males. They develop mostly on the inferior metaphysis of the femur, the pelvic bones, and the ribs. The course is slow (several years); pain appears when the tumor has attained considerable size. Metastasis is mainly to the lungs and lymph nodes. Treatment involves surgery (amputation, resection) combined with the administration of antineoplastic agents.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Traditionally, chondrosarcomas have been thought to be relatively radioresistant, due, in part, to their low-grade nature [16, 24].
Four out of seven patients with Maffucci syndrome developed other malignancies in addition to chondrosarcomas. Additionally, none of the patients in their study actually died of the skeletal sarcoma, but four out of the five total patients in their study who had a non-skeletal malignant lesion died.
[sup][16] It was also shown to sensitize chondrosarcoma cells to cisplatin-based chemotherapy, by inhibiting cell growth and apoptosis both in vitro and in vivo .
Chondrosarcoma is a malignant mesenchymal tumor that produces cartilaginous matrix.
Histopathologically, chondrosarcomas are divided into two types: conventional and variant.
Histological examination (Fig 2) showed the mass to be a chondrosarcoma (grade 1).
Extraskeletal myxoid chondrosarcoma is a rare tumour, accounting for about 2.5% of all soft tissue sarcomas.
The commonest is osteosarcoma, followed by chondrosarcoma, but Ewing's sarcoma and similar sarcomas are not unusual.
Chondrosarcomas are the second most frequent primary malignant tumours of the bone and represent one fourth of all primary bone sarcomas.
Unlike the central and periosteal chondrosarcomas, IDH1 and IDH2 mutations are not detected in EMCS.