Chondrosarcoma

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chondrosarcoma

[¦kän·drō·sär′kō·mə]
(medicine)
A malignant tumor of cartilage.

Chondrosarcoma

 

a malignant tumor of cartilage tissue, sometimes accompanied by mucous degeneration; a type of sarcoma. Chondrosarcomas most often occur in males. They develop mostly on the inferior metaphysis of the femur, the pelvic bones, and the ribs. The course is slow (several years); pain appears when the tumor has attained considerable size. Metastasis is mainly to the lungs and lymph nodes. Treatment involves surgery (amputation, resection) combined with the administration of antineoplastic agents.

References in periodicals archive ?
Chondrosarcoma of the jaw: A closer look at its management.
IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumors.
We proceeded with an open biopsy, which showed low-grade chondrosarcoma.
Hopper, "Spinal chondrosarcoma arising from a solitary lumbar osteochondroma," Journal of the Belgian Society of Radiology, vol.
Four out of seven patients with Maffucci syndrome developed other malignancies in addition to chondrosarcomas.
sup][16] It was also shown to sensitize chondrosarcoma cells to cisplatin-based chemotherapy, by inhibiting cell growth and apoptosis both in vitro and in vivo .
Chondrosarcoma is a malignant mesenchymal tumor that produces cartilaginous matrix.
Temporal bone chondrosarcomas have been mistaken for multiple sclerosis, glomus jugulare tumors, meningiomas, and chordomas.
In the end we conclude that it is feasible to make a correct cytological diagnosis of extracellular myxoid chondrosarcoma based on its distinctive features.
Although chondrosarcomas are considered the most common primary malignancy of the chest wall and sternum, it is nevertheless a rare lesion as reported in the literature.