Results: Two thousand one hundred eighty-five procedures were performed (1853 amniocenteses, 326 chorionic villus
sampling, and 6 cordocenteses).
C, Hofbauer cells are closely packed and confluent in the stroma of this CD163-stained tertiary chorionic villus
. D, CD68 staining reveals the characteristic macrophage appearance of the Hofbauer cells.
The improvised device (standard pistol grip) was mounted onto the syringe which was being used to aspirate chorionic villus
samples or other large volume aspirations.
DISCUSSION: Chorionic villus
sampling has emerged as the only safe invasive prenatal diagnostic procedure in the first trimester.
In contrast to invasive diagnostic tests like amniocentesis and chorionic villus
sampling (CVS), that carry one to two per cent risk of causing miscarriages, Veracity does not pose any threat to the foetus, Anastassiades said.
Currently, prenatal diagnosis of Wilson disease is performed by analyzing fetal cells collected by either chorionic villus
sampling or amniocentesis.
"This new method of risk assessment has resulted in a shift to first trimester diagnostic testing by way of chorionic villus
sampling (CVS) in the high-risk group of women identified by screening with nuchal translucency and serum biochemistry, and also far less diagnostic testing, which itself carries a risk of miscarriage.
However, Dr Al Hejari revealed many still chose to undergo a Chorionic Villus
Sampling (CVS) test at around 11 weeks and then get an abortion if a hereditary disease was detected, often travelling abroad for the procedure - including to Saudi Arabia, Iran and Egypt.
To contain the spread of this fatal disease, his foundation also creating awareness amongst people and advised those families where already a thalassemia patients exist to do Chorionic villus
sampling (CVS) test after three months of pregnancy and if the test was positive the doctors advised for abortion.
But it identifies fewer chromosomal abnormalities than combination screening or the more invasive chorionic villus
sampling and amniocentesis.