Since DSCC1 plays important roles in insister chromatid
cohesion, DNA replication, and cell cycle, we performed cell cycle analysis with 5-bromo-2'-deoxyuridine (BrdU) flow cytometry kit to determine the impact of DSCC1 silencing on cell cycle transition in HCC cell lines.
Cell cycle checkpoint 0.91648 39 Mitotic sister chromatid
segregation 0.91597 29 Regulation of cyclin-dependent protein 0.88779 32 serine/threonine kinase activity Reproduction 0.84575 23 DNA damage checkpoint 0.84231 26 G1/S transition of mitotic cell cycle 0.84194 34 Figure 3.
Crossen, "The incidence of sister chromatid
exchanges in cultured human lymphocytes," Mutation Research/Fundamental and Molecular Mechanisms ofMutagenesis, vol.
exchange is used as a sensitive indicator of chromosomal exposure because increased frequency of SCE also occurs with exposure to genotoxic factors at low levels.
Sevoflurane anaesthesia does not induce the formation of sister chromatid
exchanges in peripheral blood lymphocytes of children.
In the male population aneuploidies appear due to meiotic synapse abnormalities resulting in the creation of bivalent sister chromatids
which lead to abnormal sperm morphology production, or meiotic arrest.
Dicentric chromosomes (DC), acentric fragments (AF), and chromatid
breaks (ChB) were the indices used to evaluate the chromosomal aberrations during the present study.
Ionising radiation induced chromosome type of aberrations in G1, chromatid
type of aberrations in G2 and most of the S phase.
gene conversion is a prominent double-strand break repair pathway in mammalian cells.
segregation, called random chromatid
segregation and maximum equational
Moreover, tea drinking has recently proven to be associated with cell-mediated immune function of the human body (Wu et al., 2012) and protects against hepatitis C virus entry (Calland et al., 2012).Earlier studies of the antimutagenic activity of green tea were to be effective in reduction chromosomal aberrations (CAs), micronucleated polychromatic erythrocytes, sister chromatid
exchange (SCEs), gene forward mutation induced by various chemicals in both in vitro and in vivo system (Bhattacharya& Girl, 2012; Ito et al., 1989; Wang et al., 1989; Imanishi et al., 1991).