The most common neoplasms that are routinely encountered are clear cell, papillary, chromophobe
RCCs, and oncocytoma, which together account for nearly 90% of all renal cortical tumors.
A single case of chromophobe
RCC was observed in our study.
So far preoperative differentiation between oncocytomas and chromophobe
RCCs could not be done accurately using imaging methods, and both tumor types have been treated surgically.
In electron micrographs, the stellate cells looked similar to the chromophobe
cells, as they were absence of secretory granules.
Rarely, oncocytoma can occur as a part of hybrid oncocytic chromophobe
tumors (HOCT), which are a subtype of chromophobe
renal cell carcinoma (chRCC) that consist of chRCC and renal oncocytoma.
However, the differentiation between the benign oncocytoma  and its malignant counterpart, the chromophobe
renal cell carcinoma, is a continuous challenge for all diagnostic disciplines, such as radiology, urology, and pathology, since there are no absolute distinctive diagnostic criteria.
Major histopathological subtypes include clear cell carcinoma, papillary carcinoma, chromophobe
carcinoma, collecting duct carcinoma, medullary carcinoma, and unclassified categories .
renal cell carcinoma: a review of an uncommon entity," International Journal of Urology, vol.
reported that 34 (27%) of 124 patients with BHD had renal tumors with variable histology, most commonly hybrid oncocytic tumors, and chromophobe
renal cell carcinomas .
Subtypes of renal carcinoma include clear cell, papillary, chromophobe
, medullary, and collecting duct carcinoma.
He underwent transsphenoidal surgery (TSS), and the histology showed a chromophobe
adenoma with scattered single GH-positive cells and a few clusters of prolactin-positive cells, with the Ki67 index estimated at 5-10%.
Using a decision tree classifier, the identified miRNA signature showed a sensitivity of >95% for distinguishing normal from RCC and papillary RCC and showed 100% sensitivity for clear cell RCC and in distinguishing oncocytoma from chromophobe