Proper mitosis, in turn, depends on changes in chromosome organization, such as
chromosome condensation and sister chromatid cohesion.
This is caused by early onset of chromosome condensation in the early G2 of the cell cycle (so it is called premature chromosome condensation or PCC syndrome) and delayed decondensation in early G1-phase of the cell cycle.
Premature chromosome condensation syndrome is a disorder which is characterized by microcephaly, short stature, and misregulated chromosome condensation.
Mutations in microcephalin cause aberrant regulation of chromosome condensation.
Phosphorylated H2A and H4 are found in mouse spermatogenesis, and correlates with both mitotic/meiotic chromosome condensation and displacement of histone proteins from the nucleosome structure.
Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.
Makde, a postdoctoral member of the research team led by Tan, grew molecular crystals of the protein RCC1 (regulator of
chromosome condensation, a protein critical for proper separation of chromosomes during cell division) bound to the nucleosome, and used X-ray crystallography to determine the atomic structure of the complex.
For karyomorphological studies, metaphases were rigorously selected based on the level of
chromosome condensation.
Folate sensitive fragile site expression seems to appear as a result of heritable defects of DNA methylation along a region normally binding a folding protein involved in
chromosome condensation.
The karyotype formula reported here are quite different from that of Wang and Guo (2007), probably reflecting variations in
chromosome condensation and/or errors in pairing and measurement.
G-banding and
chromosome condensation in the ant, Tapinoma nigerrimum.
However, the differences appear to be minor, and may stem simply from slight differences in
chromosome condensation and/or fixation, or in interpretation of images by individual observers.
