(redirected from chronic gastritis)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.


inflammation of the lining of the stomach
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an inflammation disease of the mucosa of the stomach. The development of gastritis is caused by exogenous factors (prolonged nutritional imbalance, overeating, insufficiently varied diet, alcohol abuse, nicotine abuse, and other kinds of intoxication and infection) and endogenous factors (functional disorders of the nervous system, neural reflexes from other diseased organs, such as the intestine and the gall bladder). The form of gastritis is determined by the nature, the intensity, and the duration of the exposure to the irritant that caused the gastritis and also by the organism’s resistance and the occurrence of relapses. Types of gastritis include acute and chronic, localized and diffuse, hypertrophic, atrophic, erosive, polypous, and gastritis with a high or low acidity of the gastric mucus.

Severe gastritis develops as a result of overeating, alcohol abuse, poisoning by alkalis or acids, the intake of irritative medicines, or the ingestion of food that is mechanically irritating, spicy, or too cold or too hot or fatty food that is hard to digest; severe gastritis can also be caused by certain microbes (streptococci, staphylococci, salmonellae, etc.), which enter the organism from contaminated food. Sometimes gastritis develops as a result of the endogenous intoxication of the organism, for example, in uremia and also in cases of individual intolerance of certain foods (fish, crayfish, crab, strawberries, eggs, etc.). Acute gastritis usually begins abruptly with the appearance of an unpleasant sensation in the abdomen, burning and heaviness in the epigastrium, headache, loss of appetite, nausea, eructation, and recurrent vomiting (sometimes with bile and mucus) that brings temporary relief; in some cases symptoms include thirst, chills, and fever. As the inflammation spreads to the intestine sharp colicky pain, borborygmus, and diarrhea appear. The sickness lasts for three to five days and, as a rule, ends with recovery. But there may be relapses.

Chronic gastritis is characterized by chronic inflammation of the mucosa of the stomach with gradual atrophy. Chronic gastritis develops either as a result of frequently recurring acute gastritis or as a result of the prolonged effects on the organism of the same causes that bring about acute gastritis. Often, chronic gastritis is caused by a chronic disease (tuberculosis, hepatitis, dental caries, etc.), by a dysfunction of the central nervous system, or by a metabolic disorder; occupational hazards (working in soap factories and hot shops and candle and margarine factories; the swallowing of metallic, cotton, or coal dust) and the prolonged ingestion of certain medicines can also cause gastritis. Chronic gastritis may take its course with insufficient, normal, or increased secretion of gastric juice. In the case of gastritis with decreased secretion patients are disturbed by lack of appetite, an unpleasant astringent or metallic taste in the mouth, eructation of air or with a rotten-egg aftertaste, nausea, a sensation of heaviness in the epigastrium, and occasional vomiting soon after eating. Sharp pains appear when food is ingested into the intestine. Chronic gastritis with normal or increased secretion begins at an early age. It is accompanied by pains and heaviness in the epigastrium, persistent heartburn, acidic eructation, a burning sensation, and a sensation of pressure and bursting that usually occurs two to three hours after eating. After the ingestion of food the pains pass.

Treatment for gastritis includes the elimination of the causes of acute gastritis, regulation of the functions of the central nervous system, treatment of the underlying diseases, the elimination of focal infection, improvement of oral hygiene, and elimination of occupational hazards. Of special importance are the hygienic and sanitary measures and adequate control of the food products for sale and the preparation of food in public catering facilities. Health-resort therapy yields good results (Essentuki, Zheleznovodsk, Borzhomi, Piatigorsk, Arzni, Druskininkai, etc.).


Gordon, O. L. Khronicheskii gastrit i tak nazyvaemye funktsional’nye zabolevaniia zheludka. Moscow, 1959.
Sobakin, M. A. “Elektrograficheskoe issledovanie motornoi deiatel’nosti zheludka pri pishchevarenii v eksperimente i v klinike.” In the collection Voprosy fiziologii i patologii pishchevareniia. Moscow, 1958. Pages 141-60.


Gastritis in animals. Gastritis is observed in all animal species; in ruminants the equivalent is inflammation of the abomasum. It is caused by feeding on spoiled feeds, overfeeding, abrupt changes in diet, poisoning by poisonous plants and chemicals, tooth diseases, abnormal wearing down of teeth, and secondarily by certain infectious and parasitic diseases. The clinical aspects of gastritis include a decrease or absence of appetite, apathy, pain during palpation of the stomach, and colic; among carnivores and swine gastritis is accompanied by vomiting. In the diagnosis of gastritis the examination of the contents of the stomach obtained by means of a probe or by a needle puncture (in ruminants) is of great importance. Acute gastritis runs a course of several days and has a favorable outcome; chronic gastritis can effect permanent changes and can persist for months. Treatment focuses on elimination of the causes and prescription of an appropriate diet. In cases of intoxication, lavage of the stomach and laxatives are prescribed; for dogs and swine emetics must be used. In order to improve secretory and motor activity, Karlovy Vary salts, hydrochloric acid, pepsin, bitters, and other medicines are administered orally. Systematic veterinary and sanitary monitoring of the quality of feeds, the condition of pastures, the feed diet, and the watering places is necessary for prevention of gastritis.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Inflammation of the stomach.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
- + Noncancerous 10 10 (100)/10 (100) 0 (0)/0 (0) Premalignant 42 26 (62)/29 (69) 12 (29)/7 (17) Chronic gastritis 24 19 (79)/20 (83) 4 (17)/2 (8) Intestinal metaplasia 18 7 (39)/9 (50) 8 (44)/5 (28) Gastric cancer 74 40 (54)/42 (57) 28 (38)/13 (18) Intestinal type 48 20 (42)/22 (46) 22 (46)/9 (19) Diffuse type 26 20 (77)/20 (77) 6 (23)/4 (15) Notch1 Cytoplasm, No.
In total, 331 patients with chronic gastritis were included; they carried the MDM2 SNP309 G/G genotype and were without a history of the following: H.
In this study, the severity of chronic gastritis was mostly reported as mild (51.58%) in people with mild H.
Our findings may provide valuable insight into the pathogenesis and progression of chronic gastritis into gastric carcinoma.
The degree of acute and chronic inflammation of the lamina propria, as well as the extent of atrophy and intestinal metaplasia, were determined by using the visual analogue scales of updated Sydney system for grading chronic gastritis.
These findings support the proposal that the chronic gastritis associated with H pylori infection forms the basis from which lymphoma and/or carcinoma might develop.[3] The simultaneous presence of lymphoid follicles, atrophy, and intestinal metaplasia in an endoscopic biopsy could point to a higher risk for the development of a gastric neoplasia, and such disorders probably should be periodically watched.
pylori-induced hyperchlorhydric chronic gastritis, which is present in 85% to 100% of individuals with duodenal ulcers and in 65% with gastric ulcers.
The study between January 2001 and September 2009 comprised patients who were examined for gastric ulcer, duodenal ulcer, chronic gastritis, or gastric carcinoma, as well as those who were clinically diagnosed with upper gastrointestinal problems.
Chronic gastritis, intestinal metaplasia, and low-grade intraepithelial neoplasia were grouped into non-cancerous lesions; and early gastric cancer and high-grade intraepithelial neoplasia were grouped into cancerous lesions.
Relationship between Biliary Symptoms and UGI-Scopy Findings UGI Scopy Findings Frequency Percent Lax Cardia, Fundal Gastritis Chronic Diffuse Erosive Gastritis Lax Cardia, Grade B Esophagitis 7 10.6% Scattered Gastric Erosions in Fundus and 1 1.5% antrum 5 7.8% Periampullary Diverticulum in Second 2 3.0% part of Duodenum 1 1.5% Lax Cardia, Fundal Gastritis, Grade A 3 4.5% Esophagitis 2 3.0% Diffuse Chronic Gastritis 1 1.5% Lax Cardia, Bile Reflux Esophagitis, 1 1.5% Duodenitis.
(1, 2, 5, 8) The incidence of gastric adenocarcinoma, usually the intestinal type, is also increased in CVID and occurs on a background of chronic gastritis, diffuse intestinal metaplasia, and paucity of plasma cells in the lamina propria.
Chronic gastritis also causes changes in the cells of the gastric mucosa, leading to atrophy.

Full browser ?