Administration of DMP-2 and DMPP-5 pellets as multi-particulate formulations of DC could produce both immediate- and controlled-release profiles of DC at a predetermined time in the small intestine so as to cater for the requirements of chronotherapy
Applying the knowledge of circadian function and regulation to the relevance of disease has enabled a chronotherapy
approach in the timing of administration of conventional drugs to synchronize the rhythms in disease activity with the efficacy of the drug.
The potential applications of colonic drug delivery systems include the chronotherapy
of diseases with characteristic early morning symptoms due to their circadian rhythms [35-37].
Adjunctive triple chronotherapy
(combined total sleep deprivation, sleep phase advance, and bright light therapy) rapidly improves mood and suicidality in suicidal depressed inpatients: an open label pilot study.
To follow this chronotherapy
approach one has to wake up at 2: 00 AM to take the tablet of prednisolone.
is the scientific term used to describe medication administration to maximize effectiveness and minimize side effects according to circadian rhythms.
The university held a panel discussion on Monday to give the public the opportunity to find out about its work in this area of chronotherapy
. This is the treatment of an illness or disorder by administering a drug at a time of day when it is less toxic and more effective.
This approach, termed "adjunctive triple chronotherapy
," begins with total sleep deprivation for a period of 33-36 hours.
Targeting patho-physiological rhythms: prednisone chronotherapy
shows sustained efficacy in rheumatoid arthritis.
All this work makes the evaluation of circadian misalignment and its treatment with chronotherapy
an essential part of epilepsy care.
Sleep phase advance is a form of chronotherapy
that shifts progressively the sleeping and waking patterns of the patient and it is often associated with antidepressant treatment.