This proposal was proven in subsequent studies where intraperitoneal injection of glucose enhanced LRP1 levels on the hepatic surface and increased the uptake of chylomicron
remnant lipoprotein particles .
Benade, "Postprandial lipemia and chylomicron
clearance in athletes and in sedentary men," The American Journal of Clinical Nutrition, vol.
The effect of dietary fat load on the size and composition of chylomicrons
in thoracic duct lymph.
Cell culture studies conducted in our laboratory have demonstrated that green tea catechins upregulate the expression of the LDL-receptor--the primary receptor responsible for the uptake and removal of LDL and chylomicron
remnants from circulation (21,22).
Alternatively, the surface area of lipids, chylomicrons
, and VLDL change over time postprandially after ingesting a large amount of fat (26) and thereby could affect the blood/air partition coefficient of BD.
Given that chylomicrons
are not found in body fluid specimens from nonchyle sources, the presence of chylomicrons
in a body fluid is used to identify a chylous effusion.
Omega-3 fatty acid supplementation accelerates chylomicron
Following administration of alipogene tiparvovec, the triglyceride (TG) content of the chylomicron
fraction and the chylomicron-triglyceride (TG)/total plasma TG ratio were reduced throughout the postprandial period.
At weeks 14 and 52 post-administration, patients were given a test meal with a tracer molecule designed to monitor the breakdown of newly formed chylomicrons
in the blood.
Apo E promotes the binding of lipoproteins (LDL, VLDL, and apo E-HDL) to the LDL-R and a specific chylomicron
Triglyceride-rich lipoproteins (TRLs) include chylomicrons
remnants, VLDL, and VLDL remnants.
Remnant cholesterol is the cholesterol content of the triglyceride-rich lipoproteins composed of VLDL and intermediate density lipoprotein (IDL) in the fasting state, and of these 2 lipoproteins together with chylomicron
remnants in the nonfasting state; remnant cholesterol concentrations are therefore highly correlated with triglycerides (7, 9).