cyclosporin A

(redirected from Ciclosporin)
Also found in: Dictionary, Medical, Wikipedia.
Related to Ciclosporin: tacrolimus

cyclosporin A

[¦sī·klə‚spȯr·ən ′ā]
(biochemistry)
A cyclic peptide produced by some fungi. It inactivates helper T cells, making it useful as an immunosuppressive drug, especially in the prevention of graft rejection in transplantation surgery.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Treatment of recalcitrant hidradenitis suppurativa with oral ciclosporin. Clin Exp Dermatol.
Treatment involves the use of ciclosporin drops (which are often required lifelong) and, initially at least, artificial tear replacements and antibiotics.
Craig, "Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: Metaanalysis and meta-regression of randomised trial data," British Medical Journal, vol.
Alrubaiy et al., "Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: Pragmatic randomised trial and economic evaluation (CONSTRUCT)," Health Technology Assessment, vol.
Due to this exacerbation of IP, we began treatment with ciclosporin (0.2g/day) from the third day of hospitalization.
Ryan et al., "The BILAG multi-centre open randomized controlled trial comparing ciclosporin vs azathioprine in patients with severe SLE," Rheumatology, vol.
Initial immunosuppression is comprised of Methylprednisolone, Basiliximab 40 mg, Mycophenolate-Mofetil, and Ciclosporin. Kidney function promptly recovered and ultrasonography showed sufficient perfusion of the transplanted kidney without evidence of urine retention.
Brochard et al., "Open trial of ciclosporin treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis," British Journal of Dermatology, vol.
Bianchi, "Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment?," Nephron, vol.