cisplatin

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cisplatin

[¦sis′plat·ən]
(medicine)
A transition-metal complex that is used in the treatment of cancer, with particular effectiveness in the treatment of testicular and ovarian cancers; second- and third-generation variants of this drug have been developed to mitigate undesirable side effects.
References in periodicals archive ?
In this experiment TPA was again used to induce cell death DMSO was used as the negative control while CIS-Platinum (SIGMA product no.
SK-OV-3 cells are resistant to tumor necrosis factor and to several cytotoxic drugs including diphtheria toxin, cis-platinum, and adriamycin [1].
Deka, Solvent effect on the reactivity of CIS-platinum (II) complexes: A density functional approach, Int.
"We know that cancer cells have high levels of Cdc7 activity and can evade some DNA-damaging therapies such as cis-Platinum through Rad18 and Pol eta activity.