cisplatin


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cisplatin

[¦sis′plat·ən]
(medicine)
A transition-metal complex that is used in the treatment of cancer, with particular effectiveness in the treatment of testicular and ovarian cancers; second- and third-generation variants of this drug have been developed to mitigate undesirable side effects.
References in periodicals archive ?
Siena et al., "Gemcitabine plus Cisplatin versus Gemcitabine plus Carboplatin as First-Line Chemotherapy in Advanced Transitional Cell Carcinoma of the Urothelium: Results of a Randomized Phase 2 Trial," European Urology, vol.
Lippard, "Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin," Proceedings of the National Academy of Sciences, vol.
Due to potential risk of further cardiac complications, it was a treatment challenge as to whether we should use Cisplatin or not, in a patient with a new cardiac event as TCM.
Selenium protects cerebral cells by cisplatin induced neurotoxicity.
While strong expression in inner and outer hairy cells of organ of corti was observed in the cisplatin group, cells showing a rather strong TUNEL-positive reaction were detected (Figure 2).
Expression of LINC00261 was involved in cisplatin effect on colon cancer cells
reported on a phase II trial combining gemcitabine with ifosfamide and cisplatin (GIP) in the initial salvage treatment of 37 patients with GCT and the favorable criteria used in the MSKCC TIP study [17].
Cisplatin (10[micro]M; TEVA, Petah Tikva, Israel) pemetrexed (200[micro]M; Lilly, IN, USA) and Nutlin-3A (5, 10 or 20[micro]M; Sigma-Aldrich, MO, USA) was applied either alone or in combination.
Cisplatin Injection is indicated as therapy to be employed as follows
Cisplatin is an effective antineoplastic drug used to treat varied range of human malignancies.