class switch


Also found in: Medical.

class switch

[′klas ‚swich]
(immunology)
A switch of B-lymphocyte expression from one antibody class to another.
References in periodicals archive ?
The research team led by Tasuku Honjo, a professor of molecular biology, found that a phenomenon called class switch recombination -- a genetic conversion allowing the production of antibodies by an immune cell -- can be induced in other types of cells if a special gene called AID is activated.
According to the team, class switch recombination is a phenomenon in which B lymph cell, a type of immune cell, converts a portion of its genes to produce a different type of antibodies in response to external stimulus.
For example, in a process known as class switch recombination, immune cells called B cells rearrange their DNA.