clock gene


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clock gene

[′kläk ‚jēn]
(genetics)
Any of a number of genes that interact to determine the duration of development and lifespan.
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References in periodicals archive ?
We report the sequences of putative core clock gene products in three nudibranchs: Hermissenda crassicornis, Melibe leonina, and Tritonia diomedea.
(1998) Double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation.
showed that osteoclast-related genes, such as nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1), and cathepsin K (CTSK), showed circadian rhythmicity similar to that of clock genes, such as Bmal1, Per1, and Per2, in the femur (cancellous bone) of mice [7].
Richter et al., "Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: is the adrenal a peripheral clock responsive to melatonin?," Endocrinology, vol.
Kudo et al., "Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour," ASNNeuro, vol.
Clock genes with the effects of oscillators and endocrine and neural signals regulate circadian rhythm [24] which may be disrupted apparently by shiftwork.
The association between the CLOCK gene polymorphisms and circadian dysfunctions of PD was estimated by computing the odds ratios (ORs) and 95% confidence intervals (CIs) from a binary logistic regression analysis using the backward-stepwise method.
Based upon the abovementioned significance, mating type gene and frequency clock gene were targeted to calculate the posttranslational modifications.
They focused on the Bmal1 clock gene, which works at its peak in the afternoon, both in mice and humans.