clonal selection theory


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Related to clonal selection theory: clonal selection theory of immunity

clonal selection theory

[¦klōn·əl si′lek·shən ‚thē·ə·rē]
(immunology)
Theory to explain the specificity of the adaptive immune response according to which there is a large pool of lymphocytes, each having genetically predetermined specificity for only one of a vast array of possible antigens. Upon encountering an antigen, the lymphocytes sensitive to it reproduce much more rapidly than the others, thus leading to a build-up of antigen-specific cells large enough to mount the response.
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These classifiers were based on the clonal selection theory. The clonal selection principle is used to describe the main features of an adaptive immune response to an antigenic stimulus.
Meng and Qiuhong [23] proposed a new artificial immune algorithm based on the clonal selection theory and the structure of anti-idiotype (IAAI).
The clonal selection theory [19] is used in immunology to describe the basic features of an immune response to an antigen stimulus.