A
clonic seizure is rhythmic muscle jerking that generally starts in one area of the body.
Effects of Different Treatments on the PTZ-Induced
Clonic Seizure
However,
clonic jerks time-locked with the contralateral PLEDs could be interpreted as epilepsia partialis continua (EPC).
Benign neonatal convulsions are focal
clonic seizures or focal tonic seizures in a normal infant and no family history.
An adequate electrical dose will manifest as generalised tonic, followed by
clonic activity of skeletal muscle, accompanied by a typical seizure pattern on EEG.
The onset of
clonic and tonic actions induced by PTZ in the control animals was found to be 47.80 [+ or -] 1.69 and 72.60 [+ or -] 1.78 s, respectively.
The established drugs for treatment of partial and generalized tonic
clonic seizures are carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), primidone (Mysoline) and valproate (Depakote).
Study title: An Open-Label Study to Evaluate the Safety, Tolerability, and Exposure-Efficacy Relationship of Fycompa Oral Suspension When Administered as an Adjunctive Therapy in Pediatric Subjects (Age 4 to Less Than 12 Years) With Inadequately Controlled Partial-Onset Seizures or Primary Generalized Tonic
Clonic Seizures
Apparently her antenatal period was uneventful till she developed seizures, which were tonic and
clonic in nature, associated with tongue bite and frothing from mouth.
The mice were closely monitored during a 30-minute period following the injection of PTZ, and the latency times to the onset of myoclonic,
clonic, and tonic convulsions were recorded.
