closed reading frame
Also found in: Medical.
closed reading frame[¦klōzd ′rēd·iŋ ‚frām]
(cell and molecular biology)
A reading frame containing terminator codons that prevent the translation of subsequent nucleotides into protein. Also known as blocked reading frame.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.