clotting factor


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Related to clotting factor: hemophilia

clotting factor

[′kläd·iŋ ‚fak·tər]
(physiology)
Any of several plasma components that are involved in the clotting of blood, such as fibrinogen, prothrombin, and thromboplastin.
References in periodicals archive ?
Current treatment is replacement of the missing blood clotting factor by transfusing commercially prepared factor concentrates.
This profile included smaller waists, lower levels of potentially harmful blood fats, and lower glucose, insulin, and clotting factor levels in men.
The new treatments are recombinants DNA-derived factor VIII and factor IX to replace missing clotting factors in hemophilic patients.
Most of the boys in this study were treated with prophylactic infusions of clotting factors, and tailoring treatment protocols to sports timetables might protect them further.
Genetic aberrations with impaired synthesis or functional defects are responsible for hereditary forms of reduced clotting factor activity, as seen in hemophilias A (factor VIII), B (factor IX), and C (factor XI).
is a specialty infusion pharmacy, serving clients who require clotting factor, IVIg and other medications for complex chronic conditions.
rFIXFc, which is currently undergoing phase III clinical trials, is a fully-recombinant clotting factor designed to replace the protein that hemophilia B patients lack and to last longer in the body than other similar products.
If his prothrombin time and partial thromboplastin time are abnormal, fresh frozen plasma may help correct a clotting factor deficiency.
People with bleeding disorders do not have enough of a particular clotting factor, a protein in blood that controls bleeding, or it does not work properly.
Thawing procedures and the time course of clotting factor activity in fresh frozen plasma: a controlled laboratory investigation.
MAXY-VII is a next generation Factor VIIa clotting factor that may offer an improved dosing regimen and safety profile.
FFP thawed at high temperatures may denature clotting factors but no study has addressed the postulate of clotting factor activation in FFP thawed at high temperatures.