Interleukin-1 cluster gene
polymorphisms in childhood IgA nephropathy.
The apolipoprotein (apo) AI-CIII-AIV cluster gene
is one of such groups.
Using highly overexpressed cluster genes
as a source, canonical signaling pathways were queried by Ingenuity Pathway Analysis (IPA, QIAGEN, Redwood City, CA, http://www.qiagen.com/ingenuity).
We chose not to cluster genes
according to changes in expression levels between day 4 and day 0 because we did not want to compare day 4 cells with uncultured mature adipocytes.
There were 17 genes involved in gene transcription, including 12 histone cluster genes
. Six genes of DEGs in network participated in inflammatory and immune response.
Distance/correlation-based clustering methods cluster genes
based on the distance/correlation among their expression profiles.
All the ST1 strains had the srtF cluster genes
but, with the exception of 3 strains, not the srtG cluster genes
aeruginosa strains were encoded by a single polycistronic m-RNA, denoting the presence of a single promoter region for the expression of the cluster genes
Do Cluster genes
based on the similarity of their expression values.
Our study determined the frequencies of IL-1 cluster genes
in healthy individuals from Korea and compared then with the other populations reported.
Partially sequenced clones from the RP23 BAC library identified by database analysis as containing Cyp2a-t cluster genes
were -430G14, -174D7, -113D13, and -353B5 [GenBank accession nos.
The c-abl proto-oncogene is translocated from chromosome 9 to the breakpoint cluster region on chromosome 22.[3,4] The c-abl and breakpoint cluster genes
are juxtaposed in a head-to-tail configuration, creating a chimeric gene that is transcribed to an 8.5-kilobase mRNA and resulting in up-regulated tyrosine kinase activity. Additional chromosomal abnormalities of clonal evolution precede the development of the blastic or acute phase in 70% to 80% of CML cases.