Blood components are also dysregulated, with UFPs tending to increase blood
coagulability (Kiling et al.
Thromboelastometry used for evaluation of blood
coagulability in dogs with kidney diseases.
Platelets release thrombin, which plays a role in inflammation (34) and angiogenesis (35), and a high platelet volume allows greater
coagulability and fibrinolysis (36).
(1.) Kageyama K, Nakajima Y, Shibasaki M, Hashimoto S, Mizobe T (2007) Increased platelet, leukocyte, and endothelial cell activity are associated with increased
coagulability in patients after total knee arthroplasty.
Decreased plasma calcium ions cause diminished blood
coagulability, reduced cardiac contractility, and smooth muscle relaxation including the vascular smooth muscle, which are very sensitive to extracellular fluid (ECF) calcium ions.
Effects of perceived stress and uplifts on inflammation and
coagulability. Psychophysiology, 4(1), 154-160.
Retzinger, "Adsorption and
coagulability of fibrinogen on atheromatous lipid surfaces," Arteriosclerosis, Thrombosis, and Vascular Biology, vol.
In cases of an rAAA,
coagulability worsens because of massive hemorrhage and the presence of hematomas within the IVC or iliac vein, directly compressing the blood flow.
Other different risk factors such as
coagulability, epinephrine and norepinephrine, and alphasympathetic vasoconstriction are higher in the morning [6, 58].
Rotational Thromboelastography (ROTEM[R]) was used to measure
coagulability in whole blood as previously described [27].
Recently, plasma levels of total cholesterol have been associated with an increase in mean platelet volume [29], which reflects increased activation, metabolic reactivity, and
coagulability [30].
Proposed mechanisms about this correlation in the mentioned study include colonization of endothelial cells, a change in fat levels in serum, an increase in
coagulability and platelet aggregation and systemic inflammations.