coated pit


Also found in: Medical.

coated pit

[′kōd·əd ′pit]
(cell and molecular biology)
A cell surface depression that is coated with clathrin on its cytoplasmic surface and functions in receptor-mediated endocytosis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Tracers appeared in coated pits and large coated vesicles, endosomes of varying sizes, multivesicular bodies, and lysosomes (Hermo, 1995).
Class 5 sequence variations produce receptors that bind ligands in coated pits but fail to release them at acidic pH in endosomes, and thus do not recycle to the cell surface (13).
The remaining domains of the LDL receptor provide the sites for sugar attachment; a segment that goes across the cell membrane; and a stretch of amino acids that falls on the cytoplasmic side of the membrane and anchors the receptors to their characteristic surface sites, structures called coated pits.