Codominance

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Related to codominant: codominant inheritance

codominance

[kō′däm·ə·nəns]
(genetics)
A condition in which each allele of a heterozygous pair expresses itself fully, as in human blood group AB individuals.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Codominance

 

expression in heterozygotes of characters typical of both forms (alleles) of the gene.

Codominance is found, for example, in studying blood serum proteins (transferrins). In individuals heterozygous for the alleles controlling the biosynthesis of transferrin, both forms of this protein are present in the blood at the same time, and each form is found separately in the corresponding homozygote. The same patterns of heredity are also found in other proteins, including almost all the enzymes. The degree of activity of each of the allelic genes may be different. The products synthesized under the control of two alleles of the same gene may independently influence the expression of a character or they may interact with each other. The existence of codominance is useful in studying the genetic structure of populations without making crossings or studying pedigrees; instead, modern biochemical and immunological methods of separating proteins are used. Codominance in erythrocytic antigens facilitates the identification of blood groups in man and animals.

V. S. KIRPICHNIKOV

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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Model ACLR (n=229) % CON (n=181) % Codominant G/G 99 43.2 89 49.2 A/G 101 44.1 77 42.5 A/A 29 12.7 15 8.3 Dominant G/G 99 43.2 89 49.2 A/G-A/A 130 56.8 92 50.8 Recessive G/G-A/G 200 87.3 166 91.7 A/A 29 12.7 15 8.3 Overdominant G/G-A/A 128 55.9 104 57.5 A/G 101 44.1 77 42.5 Model OR 95% CI p * Codominant G/G 1.00 0.262/0.469 A/G 0.85 0.56 1.28 A/A 0.58 0.29 1.14 Dominant G/G 1.00 0.231/0.334 A/G-A/A 0.79 0.53 1.16 Recessive G/G-A/G 1.00 0.151/0.306 A/A 0.62 0.32 1.20 Overdominant G/G-A/A 1.00 0.751/0.731 A/G 0.94 0.63 1.39 * after a slash p value adjusted for sex; OR--odds ratio, 95% CI-- confidence intervals Table 3.
Meanwhile, Egger's test also did not show strong, statistically significant publication bias in any of the five models (codominant genetic model [C vs.
In our study, +49A>G polymorphism indicated a strong relationship with Pv in terms of minor allele frequency (OR =0.59, 95% CI = 0.38-0.92, p = 002), codominant 1 model (OR=1.54, 95% CI = 0.48-5.01 p = 004), dominant genetic model (OR = 0.54, 95% CI = 0.40-0.96, p = 003), and log-additive genetic model (OR = 0.62, 95% CI = 0.40-0.96, p = 003).
With further increase of the temperature (the third stage), more oxide films are broken and stripped away from the faying surface by codominant compressive stress and shear stress.
In the codominant model of heterozygote vs wild homozygote, the associations between rs2280091 and rs528557 polymorphisms and asthma in children were significant (OR=1.91, 95%CI=1.24-2.94, and OR=2.92, 95%CI=1.33-6.39, respectively).
Some auditor bodies reveal the score of the associated dominant and codominant verifiers with detailed justification, while the others only provide the scores and their justification up to the indicator level.
[1] Familial hypercholesterolaemia is an autosomal codominant disorder characterised by a gene dose effect, in that the individuals with two mutant LDL receptor alleles (FH Homozygous) are more affected than those with one mutant allele (FH Heterozygous).
The diagnosis of IgAN required renal biopsy showing IgA as the dominant or codominant immunoglobulin in a typical mesangial distribution in the absence of clinical and laboratory evidence for other systemic disease.
The OR values of the variable number of tandem repeat (VNTR) polymorphism were calculated from the following three models, respectively: (1) allele model (single allele versus other alleles); (2) dominant model (contained a specific allele genotype versus other genotypes); (3) codominant model (single genotype versus other genotypes).
In codominant inheritance model, the carriers of genotype TT had a higher risk of CAD compared to those of genotype TC after adjustment for the above covariates (p = 0.019, Table 3).
However, both of these groups could be further divided on the grounds of the relative dominance of Aphanocapsa with respect to its codominant species.