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Related to codon: anticodon, codon usage, Anti codon


see nucleic acidnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a coding unit, a set of three nucleotides (triplet) that determines the position of a particular amino acid in a polypeptide chain synthesized under the control of a gene. A codon is a unit of the genetic code by means of which all the genetic information is “recorded” in DNA and RNA molecules. Many amino acids have more than one codon (so-called degeneracy of the code). There are three codons which do not code amino acids; rather, they determine the beginning or end of the synthesis of a polypeptide chain.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


The basic unit of the genetic code, comprising sequential, nonoverlapping three-nucleotide sequences in messenger ribonucleic acid, each of which is translated into one amino acid; 61 of the 64 codons code for a specific protein synthesis; the other 3 are stop codons that specify termination of the growing polypeptide or protein chain.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
There was no statistically significant difference between the sexes of the patients; and the genotypes of XRCC1 gene in codon 194, codon 280, and codon 399 (p=0.248, p=0.181, p=1.000, respectively).
Thus, the C^A polymorphisms in exon 6 do not result in change at codon 156 in cases as well as controls.
The variation allele (G > A) at codon 54 of the mbl gene produces an unstable mannose binding lectin protein, which has been correlated with increment susceptibility to infections.
Many of you may remember the triplet code "lookup tables" from some textbook, telling you how each of the 64 possible three-base DNA genome elements codes for one of the 20 amino acids, or one of the three STOP codons: TTT is phenylalanine, ATC is isoleucine, and so on.
In the same way one wild type and two mutated probes are used to determine mutation at codon 315 of katG while two wild type probes and four mutation probes are used to detection mutation at -16, -15 and -8 upstream region of inhA.8
Keywords: TP53 gene, Endometriosis, Codon 72, Pakistani population, Cell cycle.
Most conventional methods do not prevent the introduction of false start/stop codon and have low capacity efficiency.
RET 631 codon mutation is seen rarely in MEN patients.
There were 70 (9.7%) isolates with MUT 3 band representing mutation at codon S531L, 6 (0.8%) isolates with MUT1 band indicating mutation at codon D516V, 5 (0.6%) isolates with MUT2A band indicating mutation at codon H526Y, 3 (0.41%) isolates with MUT2B representing mutation at codon H526D.
Such a difference of results is influenced by several factors: differences of the techniques used for detecting mutations, differences in codon of the gene that is considered codon 12 and/or 13 and/or 61 and differences in the selection and study population.