collagen disease


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Related to collagen disease: Scleroderma, Connective tissue disorder

collagen disease:

see autoimmune diseaseautoimmune disease,
any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma globulin
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; collagencollagen
, any of a group of proteins found in skin, ligaments, tendons, bone and cartilage, and other connective tissue. Cells called fibroblasts form the various fibers in connective tissue in the body.
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collagen disease

[′kä·lə·jən di‚zēz]
(medicine)
Any of various clinical syndromes characterized by widespread alterations of connective tissue, including inflammation and fibrinoid degeneration.
References in periodicals archive ?
A clinical study in the collagen disease patients developed pulmonary tuberculosis during corticosteroid administration.
Serological testing at that time had revealed hypocomplementemia, but no other collagen diseases were detected; she was also diagnosed with hypertension.
It was more closely associated with the collagen diseases such as lupus, rheumatoid arthritis, scleroderma and periarteritis nodosa.
The presence of AECAs has been reported in patients with a wide variety of diseases, including collagen diseases (Table 1), inflammatory bowel disease, diabetes, thyroid diseases, thrombotic thrombocytopenic purpura, primary sclerosing cholangitis, interstitial lung disease, chronic obstructive lung disease, uveoretinitis, renal transplantation, Susac syndrome, masked hypertension, and atherosclerosis [8-23].