collagenase


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collagenase

[′kä·lə·jə‚nās]
(biochemistry)
Any proteinase that decomposes collagen and gelatin.
References in periodicals archive ?
Collagenase clostridium histolyticum is administered by local injection directly into the Dupuytren's cord - a procedure which can be carried out in an outpatient setting.
In December 2013, collagenase Clostridium histolyticum (Xiaflex[R]) was the first FDA-approved medicine to treat PD specifically for patients with Peyronie's disease with a plaque in the penis that resulted in a curvature of at least 30 degrees upon erection.
In-vitro collagenase enzymatic degradation was performed as per the method described by Connolly et al.
In one of the two main studies, which enrolled 306 patients, 64% of those treated with collagenase clostridium had a contracture reduction of the primary joint to 0-5 degrees, 30 days after the last injection, compared with 7% among those in the placebo group.
Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-l (MMP-3) protein levels in human dermal fibroblasts.
LPL activities in cellular and stromal-vascular cells were measured in deoxycholate extracts of isolated adipocytes and preadipocytes by collagenase digestion for 1 h at 37[degrees]C.
Type IV collagenase immunoreactivity in invasive breast carcinoma.
Obviously, more comparison studies need to be conducted that contrast advanced wound debriding techniques, including those employing collagenase, because most studies to date have merely compared the newer products with gauze alone.
UV induced collagenase and elastin expression and reduced fibronectin and transforming growth factor-beta proteins in keratinocytes.
Innervated electrocytes that retain electrical responsiveness to presynaptic stimulation can be isolated from skate electric organ following collagenase treatment at room temperature (Fox et al.
Beginning this month, Healthpoint will ship commercial lots of Collagenase SANTYL([R]) Ointment produced at DPT's Lakewood facility to its North American customers.
M2 PHARMA-November 21, 2016-BioSpecifics Technologies reveals positive results from phase 2b study of collagenase clostridium histolyticum