The perforating dermatoses are a diverse group of diseases that include four types: elastosis perforans serpiginosum, Kyrle disease, perforating folliculitis, and reactive perforating collagenosis
However, single lesion frequency of reactive perforating collagenosis
(RPC), blue nevus, atrophic skin lesions, cafe-au-lait macules, melasma, macular amyloidosis, pigmented verruca vulgaris, lentigo maligna melanoma, dermatofibroma and pigmented basal cell carcinoma (BCC) was also seen, not mentioned in table.
Colloid milia in 3 cases (1.5%); 2 (1%) cases each of Lichen amyloidosis and Lichen sclerosus et atrophicus was seen; 1 (0.5%) each case of Parapsoriasis, Favre-Racouchot Syndrome, Pruritus ani, Pyogenic Granuloma, Lupus Profundus were seen, 2 (1%) cases each of reactive perforating collagenosis
and granuloma annulare and 3 (1.5%) cases of polymorphous light eruptions.
People who get skin cancer show typical signs of chronic sun damage, for example, collagenosis
, irregular pigmentation, wrinkling of the skin, telangiectasia of the skin, and solar keratosis on sun exposed areas.
Wang et al., "Morphologic changes of cerebral veins in hypertensive rats: venous collagenosis
is associated with hypertension," Journal of Stroke & Cerebrovascular Diseases, vol.
Due to the pathomechanism, the fixed arterial hypertension often coexists with collagenosis
, which was confirmed in our study.
Several different forms of perforating dermatoses exist, including reactive perforating collagenosis
and the acquired perforating dermatosis diagnostic group (often associated with diabetes mellitus or chronic renal disease), which includes acquired reactive perforating collagenosis
(RPC), elastosis perforans serpiginosa, perforating folliculitis, and Kyrle's disease.
The diagnosis of photo-onycholysis is almost clinical and can be made by exclusion of onycholysis which can be seen in other dermatologic diseases such as fungal infection, lichen planus, psoriasis, histiocytosis, atopic dermatitis, contact dermatitis, ectodermal dysplasia, collagenosis
, dysthyroidism, bronchiectasis, yellow nail syndrome, iron deficiency anemia, multiple myeloma, and neoplasia.
Among the rare causes of stroke, there lies the inflammatory arteritis of collagenosis
, in our case, the systemic lupus erythematous (SLE) [Kitagawa, 1990, Kushner M, 1989]
(2.) Yanagihara M, Fujita T, Shirasaki A, et al: The pathogenesis of the transepithelial elimination of the collagen bundles in acquired reactive perforating collagenosis
. A light and electron microscopical study.
However, there are several unknown aspects, such as why some patients with CAD have CAE while most of the patients have not and why CAE is related to other pathological entities such as collagenosis
, connective tissue diseases, and vasculitis.
Disseminated eosinophilic collagenosis
and familial eosinophilia.