In this series six cases of papillary carcinoma on cytology, four were confirmed on histopathology, remaining two were nodular colloid goiter
with cystic degeneration.
The other benign tumours encountered in the present study were extra gonadal mature teratoma, schwannoma, benign mesenchymal (BST) lesions like fibrohistiocytic lesion, solitary fibrous tumour (SFT), inflammatory pseudo tumour (IST) and colloid goiter
FNA diagnosis of HT with colloid goiter
was made in few cases (n = 5).
Among them colloid goiter
was the most common followed by benign cystic lesion.
The commonest benign pathological lesion encountered was colloid goiter
accounting for 60% of all thyroid lesions.
Limitation of thyroid FNAC we faced in this study is that: Since there is a group of lesions which overlap benign and malignant features, for instance, the distinction between a cellular colloid goiter
and a follicular lesion was impossible so such cases had been excluded from the study [12,13].
The results in Table 2 show that 81.64% of the thyroid FNACs were cytologically benign and colloid goiter
Following the clinical examination, our differential diagnoses were colloid goiter
, branchial cyst, and thyroglossal duct cyst.
Of the 100 cases, 57% cases were colloid goiter
, 9% lymphocytic thyroiditis, 4% Hashimoto's thyroiditis, 6% Graves' disease, 6% follicular neoplasm, and 2% papillary carcinoma.
The diagnosis of Hashimoto's thyroiditis was confirmed by finding lymphocytic infiltrates in clusters of follicular epithelial cell, Hurthle cell changes and increased number of lymphocytes in the background and of colloid goiter
by the presence of cohesive monolayer sheets or poorly cohesive clusters of follicular epithelial cells, bare nuclei, macrophages and abundant colloid, multinucleated giant cells, epithelioid cell clusters and anisonucleosis.
10: Peritumoral morphology in thyroid neoplasms lympocytic infiltrate 23.30% colloid goiter
23% multimodular goiter 19.20% Hashimoto thyroiditis 11.50% multicentricity 11.50% Hurthle cell change 11.50% Note: Table made from pie chart.
Case 1: Cytological smears showed abundant colloid with moderate number of follicular cells arranged in sheets and occasional macrophages favoring the diagnosis of nodular colloid goiter
. Histology of this case showed the presence of microscopic focus of papillary carcinoma 8 mm in diameter.